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Hazara orthonairovirus information


Hazara orthonairovirus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Nairoviridae
Genus: Orthonairovirus
Species:
Hazara orthonairovirus
Strains[1]
  • Hazara virus
  • Tofla virus

In 1954 the Hazara orthonairovirus, one of the 34 tick-borne viruses of the genus Orthonairovirus, was discovered in Pakistan in the Ixodes tick native to that region.[2][3] Today this virus is studied in mice in an attempt to develop treatments for the highly pathogenic Crimean-Congo Hemorrhagic Fever virus.[4]

  1. ^ Kuhn, Jens H.; et al. (21 September 2016). "Create five (5) new species in the genus Nairovirus(proposed family Nairoviridae, proposed order Bunyavirales), rename the genus Orthonairovirus, and rename all existing species" (PDF). International Committee on Taxonomy of Viruses (ICTV). p. 11. Retrieved 1 April 2019.
  2. ^ Begum, F.; Wisseman Jr., C. L.; Casals, J. (1970). "Tick-borne viruses of the West Pakistan: II. Hazara virus, a new agent isolated from Ixodes redikorzevi ticks from the Kaghan Valley, W. Pakistan12". American Journal of Epidemiology. 92 (3): 192–194. doi:10.1093/oxfordjournals.aje.a121197. PMID 5458947.
  3. ^ Flusin, O.; Vigne, S.; Peyrefitte, C. N.; Bouloy, M.; Crance, J.-M.; Iseni, F. (2011). "Inhibition of Hazara nairovirus replication by small interfering RNAs and their combination with ribavirin". Virology Journal. 8 (1): 249. doi:10.1186/1743-422X-8-249. PMC 3120786. PMID 21600011.
  4. ^ Dowall, S. D.; Findlay-Wilson, S.; Rayner, E.; Pearson, G.; Pickersgill, J.; Rule, A.; Merredew, N.; Smith, H.; Chamberlain, J.; Hewson, R. (2011). "Hazara virus infection is lethal for adult type I interferon receptor-knockout mice and may act as a surrogate for infection with the human-pathogenic Crimean-Congo hemorrhagic fever virus". Journal of General Virology. 93 (3): 560–564. doi:10.1099/vir.0.038455-0. PMID 22090213.

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Hazara orthonairovirus

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In 1954 the Hazara orthonairovirus, one of the 34 tick-borne viruses of the genus Orthonairovirus, was discovered in Pakistan in the Ixodes tick native...

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Orthonairovirus

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Tofla virus

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The Tofla virus is a strain of Hazara orthonairovirus in the genus Orthonairovirus belonging to the Crimean-Congo hemorrhagic fever serogroup. It was...

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