double-strand break repair via nonhomologous end joining
telomere capping
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
8290
n/a
Ensembl
ENSG00000168148 ENSG00000285435
n/a
UniProt
Q16695
n/a
RefSeq (mRNA)
NM_003493
n/a
RefSeq (protein)
NP_003484
n/a
Location (UCSC)
Chr 1: 228.42 – 228.43 Mb
n/a
PubMed search
[2]
n/a
Wikidata
View/Edit Human
Histone H3.1t is a protein that in humans is encoded by the HIST3H3 gene.[3][4]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.[5]
Histone H3.1t is a protein that in humans is encoded by the HIST3H3 gene. Histones are basic nuclear proteins that are responsible for the nucleosome...