dentate gyrus of hippocampal formation granule cell
superior frontal gyrus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
iron ion binding
oxygen binding
protein binding
heme binding
metal ion binding
oxygen carrier activity
peroxidase activity
haptoglobin binding
organic acid binding
Cellular component
hemoglobin complex
haptoglobin-hemoglobin complex
Biological process
oxygen transport
hydrogen peroxide catabolic process
protein heterooligomerization
cellular oxidant detoxification
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
3049
544763
Ensembl
ENSG00000086506
ENSMUSG00000073063
UniProt
P09105
Q3U0A6
RefSeq (mRNA)
NM_005331
NM_001033981
RefSeq (protein)
NP_005322
NP_001029153
Location (UCSC)
Chr 16: 0.18 – 0.18 Mb
Chr 11: 32.24 – 32.24 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene.[5][6]
Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000086506 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000073063 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ (May 1989). "A review of the molecular genetics of the human alpha-globin gene cluster". Blood. 73 (5): 1081–104. doi:10.1182/blood.V73.5.1081.1081. PMID 2649166.
Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Theta-globin mRNA is found in human fetal erythroid tissue but not...