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Guvacoline information


Guvacoline
Names
Preferred IUPAC name
Methyl 1,2,5,6-tetrahydropyridine-3-carboxylate
Identifiers
CAS Number
  • 495-19-2
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:80754
ChEMBL
  • ChEMBL268808
ChemSpider
  • 141033
KEGG
  • C16821
PubChem CID
  • 160492
UNII
  • YT3OF85P98
CompTox Dashboard (EPA)
  • DTXSID20197805 Edit this at Wikidata
InChI
  • InChI=1S/C7H11NO2/c1-10-7(9)6-3-2-4-8-5-6/h3,8H,2,4-5H2,1H3
    Key: DYPLDWLIOGXSSE-UHFFFAOYSA-N
SMILES
  • COC(=O)C1=CCCNC1
Properties
Chemical formula
 C7H11NO2
Molar mass 141.170 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Guvacoline is a compound with the chemical formula C7H11NO2.[1] It is a component of Areca nut and a precursor of guvacine. It agonizes musacarinic receptors just like arecoline but unlike arecoline it lacks nicotinic activity.[2]

  1. ^ PubChem. "Guvacoline". pubchem.ncbi.nlm.nih.gov. Retrieved 2020-06-14.
  2. ^ Horenstein NA, Quadri M, Stokes C, Shoaib M, Papke RL (May 2019). "Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds". Nicotine & Tobacco Research. 21 (6): 805–812. doi:10.1093/ntr/ntx187. PMC 6528145. PMID 29059390.

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Guvacoline

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Guvacoline is a compound with the chemical formula C7H11NO2. It is a component of Areca nut and a precursor of guvacine. It agonizes musacarinic receptors...

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Guvacine

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N-demethylated derivative of arecaidine and the product of ester hydrolysis of guvacoline, both of which are also found in areca nuts as well. It is also an inhibitor...

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C7H11NO2

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g/mol, exact mass: 141.0790 u) may refer to: Arecaidine Ethosuximide Guvacoline Hypoglycin A This set index page lists chemical structure articles associated...

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Areca nut

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There are other compounds, such as arecaidine, guvacine, isoguvacine, and guvacoline. Tannins present in betel nut are mainly proanthocyanidins along with...

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Areca alkaloids

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content. Other representatives include arecaidine, guvacoline, and guvacine. Arecoline Arecaidine Guvacoline Guvacine The total alkaloid content of the nuts...

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