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Grifolin information


Grifolin
Names
Preferred IUPAC name
5-Methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzene-1,3-diol
Identifiers
CAS Number
  • 6903-07-7 ☒N
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL487804
ChemSpider
  • 4522608
PubChem CID
  • 5372312
CompTox Dashboard (EPA)
  • DTXSID401044417 Edit this at Wikidata
InChI
  • InChI=1S/C22H32O2/c1-16(2)8-6-9-17(3)10-7-11-18(4)12-13-20-21(23)14-19(5)15-22(20)24/h8,10,12,14-15,23-24H,6-7,9,11,13H2,1-5H3/b17-10+,18-12+
    Key: PZHNKNRPGLTZPO-VZRGJMDUSA-N
  • InChI=1/C22H32O2/c1-16(2)8-6-9-17(3)10-7-11-18(4)12-13-20-21(23)14-19(5)15-22(20)24/h8,10,12,14-15,23-24H,6-7,9,11,13H2,1-5H3/b17-10+,18-12+
    Key: PZHNKNRPGLTZPO-VZRGJMDUBE
SMILES
  • CC1=CC(=C(C(=C1)O)C/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)O
Properties
Chemical formula
C22H32O2
Molar mass 328.496 g·mol−1
Melting point 41 °C (106 °F; 314 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Grifolin is an isolate of the mushroom Albatrellus confluens which upregulates DAPK1 in vitro.[1]

  1. ^ Luo, XJ; Li, LL; Deng, QP; Yu, XF; Yang, LF; Luo, FJ; Xiao, LB; Chen, XY; Ye, M; Liu, JK; Cao, Y (2011). "Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells". European Journal of Cancer. 47 (2): 316–25. doi:10.1016/j.ejca.2010.09.021. PMID 20943371.

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Grifolin

Last Update:

Grifolin is an isolate of the mushroom Albatrellus confluens which upregulates DAPK1 in vitro. Luo, XJ; Li, LL; Deng, QP; Yu, XF; Yang, LF; Luo, FJ; Xiao...

Word Count : 77

C22H32O2

Last Update:

the following organic compounds: Allyltestosterone Docosahexaenoic acid Grifolin 17α-Methylprogesterone Parahexyl Promestriene Retinyl acetate Tetrahydrocannabihexol...

Word Count : 57

Albatrellus confluens

Last Update:

mushroom can become a green-yellow color. This mushroom also produces Grifolin, an anticancer molecule. The species is inedible. Albatrellus subrubescens...

Word Count : 165

Phellodon niger

Last Update:

phellodonin (2',3'-diacetoxy-3,4,5',6',4''-pentahydroxy-p-terphenyl); grifolin; and 4-O-methylgrifolic acid. Additional nigernins (C through F) were reported...

Word Count : 1437

Anthony Barrett

Last Update:

total synthesis: Conversion of geraniol and farnesol into amorphastilbol, grifolin and grifolic acid by dioxinone- β -keto-acylation, palladium catalyzed...

Word Count : 2203

Phellodon

Last Update:

phellodonin; 2',3'-diacetoxy-3,4,5',6',4''-pentahydroxy-p-terphenyl; grifolin; and 4-O-methylgrifolic acid. P. niger has also been used for mushroom...

Word Count : 2946

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