Granular corneal dystrophy type I, Numerous irregular shaped discrete crumb-like corneal opacities
Specialty
Ophthalmology
Granular corneal dystrophy type II, Variable sized crumb-like opacities in the corneal stroma that have become fused in areas giving rise to elongated and stellate shapes
Granular corneal dystrophy is a slowly progressive corneal dystrophy that most often begins in early childhood.
Granular corneal dystrophy has two types:
Granular corneal dystrophy type I, also corneal dystrophy Groenouw type I, is a rare form of human corneal dystrophy. It was first described by German ophthalmologist Arthur Groenouw in 1890.[1]
Granular corneal dystrophy type II, also called Avellino corneal dystrophy or combined granular-lattice corneal dystrophy[2] is also a rare form of corneal dystrophy. The disorder was first described by Folberg et al. in 1988. The name Avellino corneal dystrophy comes from the first four patients in the original study each tracing their family origin to the Italian province of Avellino.[3]
^Online Mendelian Inheritance in Man (OMIM): 121900
^Online Mendelian Inheritance in Man (OMIM): 607541
^Folberg R, Alfonso E, Croxatto JO, Driezen NG, Panjwani N, Laibson PR, Boruchoff SA, Baum J, Malbran ES, Fernandez-Meijide R (January 1988). "Clinically atypical granular corneal dystrophy with pathologic features of lattice-like amyloid deposits. A study of these families". Ophthalmology. 95 (1): 46–51. doi:10.1016/s0161-6420(88)33226-4. PMID 3278259.
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