Crypt cell carcinoma, neuroendocrine tumour with goblet cell differentiation
Micrograph showing a goblet cell carcinoid. H&E stain.
The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
^van Eeden S, Offerhaus GJ, Hart AA, et al. (December 2007). "Goblet cell carcinoid of the appendix: a specific type of carcinoma". Histopathology. 51 (6): 763–73. doi:10.1111/j.1365-2559.2007.02883.x. PMID 18042066.
and 13 Related for: Goblet cell carcinoid information
The gobletcellcarcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma...
Gobletcells are simple columnar epithelial cells that secrete gel-forming mucins, like mucin 2 in the lower gastrointestinal tract, and mucin 5AC in...
A carcinoid (also carcinoid tumor) is a slow-growing type of neuroendocrine tumor originating in the cells of the neuroendocrine system. In some cases...
arise from cells of the endocrine (hormonal) and nervous systems. They most commonly occur in the intestine, where they are often called carcinoid tumors...
digest and absorb nutrients; gobletcells, which secrete mucin, a substance that lubricates the wall of the organ; Paneth cells, most common in the terminal...
cecocolic orifice. A cecal carcinoid tumor is a carcinoid tumor of the cecum. An appendiceal carcinoid tumor (a carcinoid tumor of the appendix) is sometimes...
tubular in appearance with a mixture of mucus-secreting gobletcells and water-absorbing cells. These glands secrete mucus into the lumen of the colon...
are four different cell types: gobletcells, parietal cells, chief cells, and enteroendocrine cells. Mutations in any of these cell types can begin the...
primary tumor appears to arise from the MUC2 expressing gobletcells and most commonly from these cells in the appendix. The K-Ras and p53 genes may be involved...
Mucinous cystadenocarcinoma Atypical gobletcells with focal tufting. The classification of these rare neoplasms is difficult and controversial. There...
II pneumocytes, bronchiolar surface cells, bronchial gland cells, or gobletcells. Most FA's are well or moderately differentiated tumors, although high-grade...