Molecular substituent derived from cyclic monosaccharides
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The β-D-glucopyranosyl group which is obtained by the removal of the hemiacetal hydroxyl group from β-D-glucopyranose
In organic chemistry, a glycosyl group is a univalent free radical or substituent structure obtained by removing the hydroxyl (−OH) group from the hemiacetal (−CH(OH)O−) group found in the cyclic form of a monosaccharide and, by extension, of a lower oligosaccharide. Glycosyl groups are exchanged during glycosylation from the glycosyl donor, the electrophile, to the glycosyl acceptor, the nucleophile.[1] The outcome of the glycosylation reaction is largely dependent on the reactivity of each partner.[2] Glycosyl also reacts with inorganic acids, such as phosphoric acid, forming an ester such as glucose 1-phosphate.[3]
^Crich, David (2010-08-17). "Mechanism of a Chemical Glycosylation Reaction". Accounts of Chemical Research. 43 (8): 1144–1153. doi:10.1021/ar100035r. ISSN 0001-4842. PMID 20496888.
^van der Vorm, Stefan; van Hengst, Jacob M. A.; Bakker, Marloes; Overkleeft, Herman S.; van der Marel, Gijsbert A.; Codée, Jeroen D. C. (2018-07-02). "Mapping the Relationship between Glycosyl Acceptor Reactivity and Glycosylation Stereoselectivity". Angewandte Chemie International Edition. 57 (27): 8240–8244. doi:10.1002/anie.201802899. ISSN 1433-7851. PMC 6032835. PMID 29603532.
^Davies, Gideon; Henrissat, Bernard (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
In organic chemistry, a glycosyl group is a univalent free radical or substituent structure obtained by removing the hydroxyl (−OH) group from the hemiacetal...
A glycosyl donor is a carbohydrate mono- or oligosaccharide that will react with a suitable glycosyl acceptor to form a new glycosidic bond. By convention...
from an activated nucleotide sugar (also known as the "glycosyl donor") to a nucleophilic glycosyl acceptor molecule, the nucleophile of which can be oxygen-...
In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalyze the hydrolysis of glycosidic...
Enzyme catalysis is the increase in the rate of a process by a biological molecule, an "enzyme". Most enzymes are proteins, and most such processes are...
Glycosylphosphatidylinositol (pronunciation) or glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein...
chemical glycosylation reaction involves the coupling of a glycosyl donor, to a glycosyl acceptor forming a glycoside. If both the donor and acceptor...
A glycosyl acceptor is any suitable nucleophile-containing molecule that will react with a glycosyl donor to form a new glycosidic bond. By convention...
machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United...
consisting of a glycosyl group attached to an amino group, -NR2. They are also known as N-glycosides, as they are a type of glycoside. Glycosyl groups can...
catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor)...
CAZypedia, an online encyclopedia of carbohydrate active enzymes. Family 32 glycosyl hydrolases comprise two distinct domains. The N-terminal domain, which...
Glycosylases (EC 3.2) are enzymes that hydrolyze glycosyl compounds. They are a type of hydrolase (EC 3). In turn, glycosylases are divided into two groups:...
matrix and eject biofilm cells forcibly. First shown in P. aeruginosa, a glycosyl hydrolase PslG can trigger biofilm disassembly by disrupting exopolysaccharide...
processes. The generation of carbohydrate structures involves linking glycosyl groups like monosaccharides or oligosaccharides through glycosidic bonds...
IUPAC, the name "C-glycoside" is a misnomer; the preferred term is "C-glycosyl compound". The given definition is the one used by IUPAC, which recommends...
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