GlnALG operon information

The glnALG operon is an operon that regulates the nitrogen content of a cell. It codes for the structural gene glnA the two regulatory genes glnL and glnG. glnA encodes glutamine synthetase, an enzyme which catalyzes the conversion of glutamate and ammonia to glutamine, thereby controlling the nitrogen level in the cell. glnG encodes NR_I which regulates the expression of the glnALG operon at three promoters, which are glnAp1, glnAp2 located upstream of glnA) and glnLp (intercistronic glnA-glnL region). glnL encodes NR_II which regulates the activity of NR_I.^[1] No significant homology is found in Eukaryotes.

^ Miranda-Rfos, Juan; Ray Sanchez-Pescador; Mickey Urdea; Alejandro A.Covarrubias (March 25, 1987). "The complete nudeotide sequence of the gfnALG operon of Escherichia coU K12|". Nucleic Acids Research. 15 (6): 2757–2770. doi:10.1093/nar/15.6.2757. PMC 340682. PMID 2882477.

[1] Miranda-Rfos, Juan; Ray Sanchez-Pescador; Mickey Urdea; Alejandro A.Covarrubias (March 25, 1987). "The complete nudeotide sequence of the gfnALG operon of Escherichia coU K12|". Nucleic Acids Research. 15 (6): 2757–2770. doi:10.1093/nar/15.6.2757. PMC 340682. PMID 2882477.