Not to be confused with Deep-sea gigantism or Island gigantism.
Medical condition
Gigantism
Other names
Giantism
Robert Wadlow stood 8 ft 11 in (2.72 m)
Specialty
Endocrinology
Symptoms
Abnormal growth in height or size, weakness and insomnia
Complications
Excessive sweating, delayed puberty, weakness and severe or recurrent headaches, strokes, vomiting or nausea, high fevers, sleepiness, dry mouth, frequent diarrheas, stomachaches, ear pains, memory loss, back pains, excessive muscle cramps, chest pains
Causes
Hyperplasia in the pituitary gland
Treatment
Surgically remove the enlarged pituitary gland
Medication
Octreotide, lanreotide or pegvisomant
Gigantism (Greek: γίγας, gígas, "giant", plural γίγαντες, gígantes), also known as giantism, is a condition characterized by excessive growth and height significantly above average. In humans, this condition is caused by over-production of growth hormone in childhood.[1][2][3][4][5]
It is a rare disorder resulting from increased levels of growth hormone before the fusion of the growth plate which usually occurs at some point soon after puberty. This increase is most often due to abnormal tumor growths on the pituitary gland.[6][7] Gigantism should not be confused with acromegaly, the adult form of the disorder, characterized by somatic enlargement specifically in the extremities and face.[8][9]
^Capatina, Cristina; Wass, John A. H. (August 2015). "60 YEARS OF NEUROENDOCRINOLOGY: Acromegaly". The Journal of Endocrinology. 226 (2): T141–160. doi:10.1530/JOE-15-0109. ISSN 1479-6805. PMID 26136383.
extremities and face. Gigantism is characterized by an excess of growth hormone (GH). The excess of growth hormone that brings about gigantism is virtually always...
Muisky Gigant, a mountain in Buryatia Flettner Gigant, an experimental German helicopter Gigant Neo (b. 1998), a Swedish breeding stallion Gigantism This...
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DamnInteresting.com, 1 December 2005. Hirsch, Oskar (1961). "Two Different Types of Gigantism Due to Similar Tumors. Discussion of Growth". Stereotactic and Functional...
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premature death if unchecked. The disease which is often also associated with gigantism, is difficult to diagnose in the early stages and is frequently missed...
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