Global InformationGeranyltranstransferase information
| geranyltranstransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.10 | ||||||||
| CAS no. | 37277-79-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a geranyltranstransferase (EC 2.5.1.10) is an enzyme that catalyzes the chemical reaction
- geranyl diphosphate + isopentenyl diphosphate diphosphate + trans,trans-farnesyl diphosphate
Thus, the two substrates of this enzyme are geranyl diphosphate (a 10 carbon precursor) and isopentenyl diphosphate (a 5 carbon precursor) whereas its two products are diphosphate and trans,trans-farnesyl diphosphate (a 15 carbon product).[1]
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups.
- ^ Lynen F, Agranoff BW, Eggerer H, Henning U, Möslein EM (1959). "Zur Biosynthese der Terpene. VI gamma,gamma-Dimethyl-allyl-pyrophosphat und Geranyl-pyrophosphat, biologische Vorstufen des Squalens". Angew. Chem. 71 (21): 657–663. doi:10.1002/ange.19590712102.