Global InformationGenomic phylostratigraphy information
Genomic phylostratigraphy is a novel genetic statistical method developed in order to date the origin of specific genes by looking at its homologs across species. It was first developed by Ruđer Bošković Institute in Zagreb, Croatia.[1] The system links genes to their founder gene, allowing us to then determine their age. This could help us better understand many evolutionary processes such as patterns of gene birth throughout evolution, or the relationship between the age of a transcriptome throughout embryonic development. Bioinformatic tools like GenEra have been developed to calculate relative gene ages based on genomic phylostratigraphy.[2]
- ^ Domazet-Loso T, Brajković J, Tautz D (November 2007). "A phylostratigraphy approach to uncover the genomic history of major adaptations in metazoan lineages". Trends in Genetics. 23 (11): 533–539. doi:10.1016/j.tig.2007.08.014. PMID 18029048.
- ^ Barrera-Redondo, Josué; Lotharukpong, Jaruwatana Sodai; Drost, Hajk-Georg; Coelho, Susana M. (24 March 2023). "Uncovering gene-family founder events during major evolutionary transitions in animals, plants and fungi using GenEra". Genome Biology. 24 (1): 1552–1554. doi:10.1186/s13059-023-02895-z. PMC 10037820. PMID 10037820.