GPR37L1 information

GPR37L1
Identifiers
Aliases	GPR37L1, ET(B)R-LP-2, ETBR-LP-2, G protein-coupled receptor 37 like 1, ETBRLP2
External IDs	OMIM: 617630; MGI: 1928503; HomoloGene: 3500; GeneCards: GPR37L1; OMA:GPR37L1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	202,133,592 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	135,095,419 bp
RNA expression pattern
	Top expressed in
	caudate nucleus; ; internal globus pallidus; ; amygdala; ; putamen; ; nucleus accumbens; ; endothelial cell; ; cingulate gyrus; ; Brodmann area 9; ; external globus pallidus; ; hippocampus proper;
	Top expressed in
	cerebellar vermis; ; dorsal tegmental nucleus; ; medulla oblongata; ; superior colliculus; ; globus pallidus; ; medial vestibular nucleus; ; inferior colliculus; ; optic nerve; ; ventral tegmental area; ; pontine nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptide binding; G protein-coupled peptide receptor activity; protein binding; G protein-coupled receptor activity; signal transducer activity; prosaposin receptor activity;
Cellular component	integral component of membrane; plasma membrane; receptor complex; membrane; cell projection; ciliary membrane;
Biological process	positive regulation of cerebellar granule cell precursor proliferation; negative regulation of astrocyte differentiation; negative regulation of hydrogen peroxide-induced cell death; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of neuron differentiation; negative regulation of smoothened signaling pathway; positive regulation of MAPK cascade; signal transduction; G protein-coupled receptor signaling pathway; negative regulation of systemic arterial blood pressure;
	Sources:Amigo / QuickGO
Orthologs
	9283
	171469
	ENSG00000170075
	ENSMUSG00000026424
	O60883
	Q99JG2
	NM_004767
	NM_134438
	NP_004758
	NP_602320
	Wikidata
View/Edit Human	View/Edit Mouse

Endothelin B receptor-like protein 2 is a protein that in humans is encoded by the GPR37L1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170075 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026424 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Valdenaire O, Giller T, Breu V, Ardati A, Schweizer A, Richards JG (Apr 1998). "A new family of orphan G protein-coupled receptors predominantly expressed in the brain". FEBS Lett. 424 (3): 193–6. doi:10.1016/S0014-5793(98)00170-7. PMID 9539149. S2CID 7999925.
^ "Entrez Gene: GPR37L1 G protein-coupled receptor 37 like 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170075 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026424 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9539149-5] Valdenaire O, Giller T, Breu V, Ardati A, Schweizer A, Richards JG (Apr 1998). "A new family of orphan G protein-coupled receptors predominantly expressed in the brain". FEBS Lett. 424 (3): 193–6. doi:10.1016/S0014-5793(98)00170-7. PMID 9539149. S2CID 7999925.

[entrez-6] "Entrez Gene: GPR37L1 G protein-coupled receptor 37 like 1".