GABBR1 information

GABBR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4MQE, 4MQF, 4MR7, 4MR9, 4MRM, 4MS1, 4MS3, 4MS4, 4PAS
Identifiers
Aliases	GABBR1, GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2, gamma-aminobutyric acid type B receptor subunit 1
External IDs	OMIM: 603540 MGI: 1860139 HomoloGene: 1132 GeneCards: GABBR1
Gene location (Human)
Chr.	Chromosome 6 (human)
End	29,633,976 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,385,959 bp
RNA expression pattern
	Top expressed in
	cingulate gyrus; ; Brodmann area 9; ; canal of the cervix; ; left uterine tube; ; gastric mucosa; ; ascending aorta; ; right coronary artery; ; anterior pituitary; ; tibial nerve; ; popliteal artery;
	Top expressed in
	habenula; ; superior frontal gyrus; ; entorhinal cortex; ; cerebellar cortex; ; medial dorsal nucleus; ; medial geniculate nucleus; ; olfactory tubercle; ; nucleus accumbens; ; cingulate gyrus; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; G protein-coupled GABA receptor activity; G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential;
Cellular component	cytoplasm; integral component of membrane; G protein-coupled receptor dimeric complex; postsynaptic membrane; cell projection; membrane; plasma membrane; synapse; integral component of plasma membrane; extracellular region; cell junction; dendrite; G protein-coupled receptor heterodimeric complex; presynaptic membrane; presynapse; Schaffer collateral - CA1 synapse; GABA-ergic synapse;
Biological process	gamma-aminobutyric acid signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; signal transduction; negative regulation of adenylate cyclase activity; G protein-coupled receptor signaling pathway; regulation of postsynaptic membrane potential; neuron-glial cell signaling;
	Sources:Amigo / QuickGO
Orthologs
	2550
	54393
ENSG00000237112; ENSG00000206511; ENSG00000206466; ENSG00000232632; ENSG00000232569;
	ENSG00000237051; ENSG00000204681
	ENSMUSG00000024462
	Q9UBS5
	Q9WV18
	NM_001470; NM_021903; NM_021904; NM_021905; NM_001319053
	NM_019439
	NP_001305982; NP_001461; NP_068703; NP_068704
	NP_062312
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid B receptor, 1 (GABA_B1), is a G-protein coupled receptor subunit encoded by the GABBR1 gene.

^ ^a ^b ^c ENSG00000206511, ENSG00000206466, ENSG00000232632, ENSG00000232569, ENSG00000237051, ENSG00000204681 GRCh38: Ensembl release 89: ENSG00000237112, ENSG00000206511, ENSG00000206466, ENSG00000232632, ENSG00000232569, ENSG00000237051, ENSG00000204681 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024462 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] ENSG00000206511, ENSG00000206466, ENSG00000232632, ENSG00000232569, ENSG00000237051, ENSG00000204681 GRCh38: Ensembl release 89: ENSG00000237112, ENSG00000206511, ENSG00000206466, ENSG00000232632, ENSG00000232569, ENSG00000237051, ENSG00000204681 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024462 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

GABBR1 information

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GABBR1

GABA receptor

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Sushi domain

Class C GPCR

Ubiquitin D

GABBR2