Protein G6b is a protein that in humans is encoded by the G6B gene, or C6orf25.[5][6][7]
This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.[7]
^ abcGRCm38: Ensembl release 89: ENSMUSG00000073414 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ribas G, Neville M, Wixon JL, Cheng J, Campbell RD (Jul 1999). "Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region". J Immunol. 163 (1): 278–87. doi:10.4049/jimmunol.163.1.278. PMID 10384126.
^de Vet EC, Aguado B, Campbell RD (Nov 2001). "G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2". J Biol Chem. 276 (45): 42070–6. doi:10.1074/jbc.M103214200. PMID 11544253.
^ ab"Entrez Gene: C6orf25 chromosome 6 open reading frame 25".
Protein G6b is a protein that in humans is encoded by the G6B gene, or C6orf25. This gene is a member of the immunoglobulin (Ig) superfamily and is located...
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