Functio laesa is a term used in medicine to refer to a loss of function[1][2] or a disturbance of function.[3]
It was identified as the fifth sign of acute inflammation by Galen, who added it to the four signs identified by Celsus (tumor, rubor, calor, and dolor).[4]
The attribution to Galen is disputed,[3] and has variously been attributed to Thomas Sydenham[5] and Rudolf Virchow.[6]
^"Dorlands Medical Dictionary:cardinal signs".
^"Definition: functio laesa from Online Medical Dictionary".
^ abRather LJ (March 1971). "Disturbance of function (functio laesa): The legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus". Bull N Y Acad Med. 47 (3): 303–22. PMC 1749862. PMID 5276838.
^Porth, Carol (2007). Essentials of pahtophysiology: concepts of altered health states. Hagerstown, MD: Lippincott Williams & Wilkins. p. 270. ISBN 978-0-7817-7087-3.
^Dormandy, Thomas (2006). The worst of evils: man's fight against pain. New Haven, Conn: Yale University Press. pp. 22. ISBN 0-300-11322-6.
^David Lowell Strayer; Raphael Rubin (2007). Rubin's Pathology: Clinicopathologic Foundations of Medicine 5th Edition. Hagerstown, MD: Lippincott Williams & Wilkins. p. 37. ISBN 978-0-7817-9516-6.
Functiolaesa is a term used in medicine to refer to a loss of function or a disturbance of function. It was identified as the fifth sign of acute inflammation...
swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functiolaesa). Inflammation is a generic response, and therefore is considered a...
redness/hyperemia), tumor (either clear or non-clear bordered tissue swelling), functiolaesa (diminish affected function). There may be systemic signs of infection...
inflammatory processes. He introduced the idea of a fifth symptom, functiolaesa, the loss of function of inflamed tissues. It was discovered approximately...
pain (dolor). Galen would write about the fifth, loss of function (functiolaesa). Soranus was a Greek physician born in Ephesus, who lived during the...
(Rubor) Fever (Calor) Swelling (Tumor) Pain (Dolor) Loss of function (Functiolaesa) Mechanism Tests Full blood count Leukocytosis C-reactive protein Erythrocyte...
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