Fractional flow reserve (FFR) is a diagnostic technique used in coronary catheterization. FFR measures pressure differences across a coronary artery stenosis (narrowing, usually due to atherosclerosis) to determine the likelihood that the stenosis impedes oxygen delivery to the heart muscle (myocardial ischemia).[1]
Fractional flow reserve is defined as the pressure after (distal to) a stenosis relative to the pressure before the stenosis.[2] The result is an absolute number; an FFR of 0.80 means that a given stenosis causes a 20% drop in blood pressure. In other words, FFR expresses the maximal flow down a vessel in the presence of a stenosis compared to the maximal flow in the hypothetical absence of the stenosis.
^Pijls NH, De Bruyne B, Peels K, et al. (June 1996). "Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses". N. Engl. J. Med. 334 (26): 1703–8. doi:10.1056/NEJM199606273342604. PMID 8637515.
^Hwang, Doyeon; Lee, Joo Myung; Koo, Bon-Kwon (2016). "Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve". Korean Journal of Radiology. 17 (3). The Korean Society of Radiology: 307–320. doi:10.3348/kjr.2016.17.3.307. ISSN 1229-6929. PMC 4842851. PMID 27134520.
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