This article is missing information about directional FSC (dFSC) (PMID 29236684) and 3D FSC (PMID 33368004) for evalulating anisotropy. Please expand the article to include this information. Further details may exist on the talk page.(November 2023)
In structural biology, as well as in virtually all sciences that produce three-dimensional data, the Fourier shell correlation (FSC) measures the normalised cross-correlation coefficient between two 3-dimensional volumes over corresponding shells in Fourier space (i.e., as a function of spatial frequency[1]). The FSC is the three-dimensional extension of the two-dimensional Fourier ring correlation (FRC);[2] also known as: spatial frequency correlation function.[3]
^Harauz & van Heel, 1986
^van Heel, 1982
^Saxton & Baumeister, 1982
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