The fasciculus retroflexus (FR) also known as the habenulointerpeduncular tract is a bundle of fibers located at the base of the midbrain in vertebrates.[1][2] Connected to the habenula (Hbn) and the interpeduncular nucleus (IPN), the fasciculus retroflexus is involved in a variety of bodily phenomena, some being sleep retention.[3] and drug addiction.[4] It acts as a channel through which messages are sent between the stria medullaris and the mid- and hindbrain. The fasciculus retroflexus, along with the stria medullaris, the habenula, and the medial forebrain bundle forms a unit for the transfer of neurological impulses. In this unit, the fasciculus retroflexus mediates the transfer of information for processes such as pain, pleasure, and motor control[5]
^"Ontology Lookup Service (OLS)". www.ebi.ac.uk. Retrieved 31 December 2023.
^Ramón y Cajal, Santiago (1999). Texture of the nervous system of man and the vertebrates. Wien: Springer. p. 82. ISBN 9783211830574.
^Valjakka, Antti; Vartiainen, Jukka; Tuomisto, Leena; Tuomisto, Jouni T.; Olkkonen, Hannu; Airaksinen, Mauno M. (1998-09-15). "The fasciculus retroflexus controls the integrity of REM sleep by supporting the generation of hippocampal theta rhythm and rapid eye movements in rats". Brain Research Bulletin. 47 (2): 171–184. doi:10.1016/S0361-9230(98)00006-9. ISSN 0361-9230. PMID 9820735. S2CID 31900585.
^Velasquez, Kenia; Molfese, David; Salas, Ramiro (2014). "The role of the habenula in drug addiction". Frontiers in Human Neuroscience. 8: 174. doi:10.3389/fnhum.2014.00174. ISSN 1662-5161. PMC 3975120. PMID 24734015.
^Roman, Elena; Weininger, Joshua; Lim, Basil; Roman, Marin; Barry, Denis; Tierney, Paul; O’Hanlon, Erik; Levins, Kirk; O’Keane, Veronica; Roddy, Darren (2020-06-01). "Untangling the dorsal diencephalic conduction system: a review of structure and function of the stria medullaris, habenula and fasciculus retroflexus". Brain Structure and Function. 225 (5): 1437–1458. doi:10.1007/s00429-020-02069-8. ISSN 1863-2661. PMID 32367265. S2CID 218495735.
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The fasciculusretroflexus (FR) also known as the habenulointerpeduncular tract is a bundle of fibers located at the base of the midbrain in vertebrates...
a bundle, the fasciculusretroflexus, which passes medial to the red nucleus, and, after decussating with the corresponding fasciculus of the opposite...
nuclei are a major component in the limbic system pathways. The fasciculusretroflexus pathway between the habenula and the interpeduncular nucleus is...
of structure and function of the stria medullaris, habenula and fasciculusretroflexus". Brain Structure and Function. 225 (5): 1437–1458. doi:10.1007/s00429-020-02069-8...
mammillary tract, the corpus callosum, the corticospinal tract, the fasciculusretroflexus and the fornix. In a study conducted with the plasmas of children...