Envirome information

"Envirome" is a concept that relates the core of environmental conditions with the successful biological performance of living beings. This concept was created in genetic epidemiology, in which an envirome is defined as the total set of environmental factors, both present, and past, that affect the state, and in particular the disease state, of an organism.^[1] The study of the envirome and its effects is termed enviromics. The term was first coined in the field of psychiatric epidemiology by J.C. Anthony in 1995.^[2][3] More recently, use of the term has been extended to the cellular domain, where cell functional enviromics studies both the genome and envirome from a systems biology perspective.^[4] In plants, enviromics is directly related to complex ecophysiology, in which the wide environment of the plants, into an omics scale, can be dissected and understood as a mosaic of possible growing factors and the balance of diverse resources available.^[5][6] In ecology, this concept can be related to the Shelford's law of tolerance.^[7] The enviromics (study of the enviromes) is conceived as a pillar of the Modern Plant Breeding,^[8] capable to connect the design and development of breeding goals concealing it with the agronomic targets for a climate-smart agriculture.^[9] It also has the ability to bridge the knowledge gaps between the different levels of systems biology and phenomics in the context of Gene–environment interaction.^[10]