The enolase superfamily is a superfamily of enzymes, members of which catalyse a range of reactions.
The enolase superfamily includes enzymes that catalyse a wide variety of reactions and performing diverse roles in metabolism. However, the reactions catalysed share the common chemical step of abstraction of a proton from a carbon adjacent to a carboxylic acid and a requirement of a divalent metal ion.[1] This diversity of functions is in contrast to many families of enzymes whose members catalyse similar chemical reactions on different substrates.
^Babbitt, Patricia; Hasson, Miriam; Wedekind, Joseph; Palmer, David; Barrett, William; Reed, George; Rayment, Ivan; Ringe, Dagmar; Kenyon, George; Gerlt, John (1996). "The Enolase Superfamily: A General Strategy for Enzyme-Catalyzed Abstraction of the Alpha-Protons of Carboxylic Acids". Biochemistry. 51 (35): 16489–16501. doi:10.1021/bi9616413. PMID 8987982.
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The enolasesuperfamily is a superfamily of enzymes, members of which catalyse a range of reactions. The enolasesuperfamily includes enzymes that catalyse...
isozymes readily form heterodimers.[citation needed] Enolase is a member of the large enolasesuperfamily. It has a molecular weight of 82,000–100,000 daltons...
its ability to accept protons. The bacterial MLEs belong to the enolasesuperfamily, several structures from which are known. MLEs have an identifying...
(R)-mandelate It is a member of the enolasesuperfamily of enzymes, along with muconate lactonizing enzyme and enolase. Gunsalus CF, Stanier RY, Gunsalus...
maintains a public database for experimental data (EFI-DB). The enolasesuperfamily contains evolutionarily related enzymes with a (β/α)7β‑barrel (TIM‑barrel)...
functional promiscuity produced by single substitutions in the enolasesuperfamily". Biochemistry. 42 (28): 8387–93. doi:10.1021/bi034769a. PMID 12859183...
"Isolierung und Kristallisation des Gärungsferments Enolase" [Isolation and crystallization of yeast enolase]. Biochem. Z. 310: 384–421. (2188 citations) Hagedorn...
identical to taxon-specific lens crystallins, such as ALDH1A1/ η-crystallin, α-enolase/τ-crystallin, and lactic dehydrogenase/ -crystallin. Also, the anuran corneal...
fluoride sensitive enzymes such as enolase, pyrophosphatase, the presumed fluoride exporter CrcB and a superfamily of CLC membrane proteins called EricF...
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