Global InformationEkpoma virus information
| Ekpoma viruses | |
|---|---|
Scientific classification
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| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Monjiviricetes |
| Order: | Mononegavirales |
| Family: | Rhabdoviridae |
| Genus: | Tibrovirus |
| Groups included[1] | |
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| Cladistically included but traditionally excluded taxa[1] | |
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Ekpoma viruses, including Ekpoma 1 tibrovirus (EKV-1) and Ekpoma 2 tibrovirus (EKV-2), are orphan viruses not associated with any disease. They are negative-sense RNA viruses and members of the rhabdovirus family. Both viruses were discovered in 2015 in blood samples collected from two healthy women living in Ekpoma, Nigeria.[2] EKV-2 appears to be widespread and ~45% of people living in and around Ekpoma have been previously exposed.[2] Both viruses have very broad cellular tropism and the ability to infect a wide range of human cancer cell lines.[3] Neither virus has been isolated, hindering research.
- ^ a b "Virus Taxonomy: 2018b Release". International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 3 February 2020.
- ^ a b Stremlau MH, Andersen KG, Folarin OA, et al. Discovery of novel rhabdoviruses in the blood of healthy individuals from West Africa. PLoS Negl Trop Dis. 2015;9(3):e0003631. Published 2015 Mar 17. doi:10.1371/journal.pntd.0003631
- ^ Caì Y, Yú S, Jangra RK, et al. Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry. Front Microbiol. 2019;10:856. Published 2019 Apr 26. doi:10.3389/fmicb.2019.00856