Global InformationEcthyma gangrenosum information
| Ecthyma gangrenosum | |
|---|---|
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| Specialty | Infectious diseases |
Ecthyma gangrenosum is a type of skin lesion characterized by vesicles or blisters which rapidly evolve into pustules and necrotic ulcers with undermined tender erythematous border. "Ecthyma" means a pus forming infection of the skin with an ulcer, "gangrenosum" refers to the accompanying gangrene or necrosis. It is classically associated with Pseudomonas aeruginosa bacteremia, but it is not pathognomonic.[1] Pseudomonas aeruginosa is a gram negative, aerobic bacillus.[2]
This type of skin lesion was first described in association with Pseudomonas aeruginosa by L. Barker in 1897.[3] It was given the name "ecthyma gangrenosum" by Hitschmann and Kreibich.[4]
It mostly occurs in patients with underlying immunocompromise (e.g. malignancy or HIV). Although most cases are due to Pseudomonas aeruginosa infection, there are recent reports of this skin lesion in association with other microorganisms, such as Escherichia coli, Citrobacter freundii, Klebsiella pneumoniae, various other Pseudomonas species, and Morganella morganii.[3]
- ^ Reich, Hilary L (2004). "Nonpseudomonal ecthyma gangrenosum". Journal of the American Academy of Dermatology. 50 (5): S114-7. doi:10.1016/j.jaad.2003.09.019. PMID 15097944. Retrieved 11 May 2020.
- ^ Koo, Su Han; Lee, Joon Ho; Shin, Heakyeong; Lee, Jong Im (2012-11-14). "Ecthyma Gangrenosum in a Previously Healthy Infant". Archives of Plastic Surgery. 39 (6): 673–5. doi:10.5999/aps.2012.39.6.673. ISSN 2234-6163. PMC 3518017. PMID 23233899.
- ^ a b Vaiman, M.; Lazarovitch, T.; Heller, L.; Lotan, G. (2015-04-01). "Ecthyma gangrenosum and ecthyma-like lesions: review article". European Journal of Clinical Microbiology & Infectious Diseases. 34 (4): 633–639. doi:10.1007/s10096-014-2277-6. ISSN 0934-9723. PMID 25407372. S2CID 14499246.
- ^ Kingsberry, M. (2017). "Ecthyma gangrenosum: Overview". Medscape.