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ESHAP information


ESHAP is an acronym for relatively intensive chemotherapy regimen that is used for salvage therapy in relapsed or refractory lymphomas and Hodgkin's lymphoma. In combination with monoclonal antibody Rituximab it is called R-ESHAP or ESHAP-R.[1]

R-ESHAP consists of:

  1. Rituximab, an anti-CD20-directed monoclonal antibody that kills both normal and malignant B-lymphocytes
  2. Etoposide, an epipodophyllotoxin topoisomerase inhibitor
  3. Solu-Medrol - Methylprednisolone, which is a glucocorticoid that can lyse lymphocytes
  4. High-dose Ara-C - cytarabine
  5. Platinol - Cisplatin, a platinum-based antineoplastic agent, also an alkylating antineoplastic agent.
  1. ^ ESHAP--an effective chemotherapy regimen in refractory and relapsing lymphoma: a 4-year follow-up study.

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ESHAP

Last Update:

combination with monoclonal antibody Rituximab it is called R-ESHAP or ESHAP-R. R-ESHAP consists of: Rituximab, an anti-CD20-directed monoclonal antibody...

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Lymphoid leukemia

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López-Guillermo A (May 2008). "Intensive chemotherapy (high-dose CHOP/ESHAP regimen) followed by autologous stem-cell transplantation in previously...

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Chemotherapy regimen

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lymphomas ESHAP etoposide, methylprednisolone (a steroid hormone), cytarabine (ara-C), platinum agent Non-Hodgkin lymphoma ESHAP-R or R-ESHAP etoposide...

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Langerhans cell sarcoma

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regimens include MAID (mesna, doxorubicin, ifosfamide, and dacarbazine), ESHAP (etoposide, carboplatin, cytarabine, and methylprednisolone), EPIG (etoposide...

Word Count : 1574

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