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Duodenal atresia information


Duodenal atresia
Radiograph of abdomen with double-bubble sign from duodenal atresia
SpecialtyPediatric gastroenterology, Pediatric surgery
SymptomsAntenatal period: polyhydramnios Neonatal period: bilious or non-bilious vomiting within first 36 hours of life, abdominal distension, lack of stooling
Usual onsetDuring embryological development
CausesUnknown
Risk factorsDown syndrome
Differential diagnosisannular pancreas, duodenal stenosis
Treatmentnasogastric suction, surgery (duodenoduodenostomy)

Duodenal atresia is the congenital absence or complete closure of a portion of the lumen of the duodenum. It causes increased levels of amniotic fluid during pregnancy (polyhydramnios) and intestinal obstruction in newborn babies. Newborns present with bilious or non-bilous vomiting (depending on where in the duodenum the obstruction is) within the first 24 to 48 hours after birth, typically after their first oral feeding. Radiography shows a distended stomach and distended duodenum, which are separated by the pyloric valve, a finding described as the double-bubble sign.

Treatment includes suctioning out any fluid that is trapped in the stomach, providing fluids intravenously, and surgical repair of the intestinal closure.

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