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Dithranol information


Dithranol
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy
category
  • AU: B2
Routes of
administration		topical
ATC code
  • D05AC01 (WHO)
Legal status
Legal status
  • UK: P (Pharmacy medicines)
Pharmacokinetic data
Bioavailability0%, trace amounts metabolites
Protein binding0%
Metabolismabsorbed and oxidised within the skin
Elimination half-lifen/a
Excretionn/a
Identifiers
IUPAC name
  • 1,8-dihydroxy-9,10-dihydroanthracen-9-one
CAS Number
  • 1143-38-0 checkY
PubChem CID
  • 2202
ChemSpider
  • 2117 checkY
UNII
  • U8CJK0JH5M
KEGG
  • D00233 checkY
ChEBI
  • CHEBI:37510 checkY
ChEMBL
  • ChEMBL46469 checkY
CompTox Dashboard (EPA)
  • DTXSID7024538 Edit this at Wikidata
ECHA InfoCard100.013.216 Edit this at Wikidata
Chemical and physical data
FormulaC14H10O3
Molar mass226.231 g·mol−1
3D model (JSmol)
  • Interactive image
Melting point178 °C (352 °F)
SMILES
  • O=C2c1c(O)cccc1Cc3c2c(O)ccc3
InChI
  • InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2 checkY
  • Key:NUZWLKWWNNJHPT-UHFFFAOYSA-N checkY
  (verify)

Dithranol (INN) or anthralin (USAN and former BAN) is a hydroxyanthrone, anthracene derivative, and is used in medications applied to the skin of people with psoriasis. It is available as creams, ointment or pastes in 0.1 to 2% strengths (Drithocreme, Dithrocream, Zithranol-RR, Micanol, Psorlin, Dritho-Scalp, Anthraforte, Anthranol and Anthrascalp). The terms dithranol and anthralin are sometimes used synonymously.

and 18 Related for: Dithranol information

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Dithranol

Last Update:

Dithranol (INN) or anthralin (USAN and former BAN) is a hydroxyanthrone, anthracene derivative, and is used in medications applied to the skin of people...

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Keratolytic

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hygroscopic property. Treatment of warts by keratolysis Chemical peel Dithranol Retinoid "Keratolytic". Merriam-Webster.com Dictionary. Retrieved 2016-01-22...

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ATC code D05

Last Update:

Drugs for keratoseborrheic disorders, topical use". D05AC01 Dithranol D05AC51 Dithranol, combinations D05AD01 Trioxysalen D05AD02 Methoxsalen In ATCvet...

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Psoriasis

Last Update:

clear affected skin of plaques. Ointment and creams containing coal tar, dithranol, corticosteroids (i.e. desoximetasone), fluocinonide, vitamin D3 analogues...

Word Count : 12976

Diazepam

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 9994

C14H10O3

Last Update:

226.23 g/mol, exact mass: 226.0630 u) may refer to: Benzoic anhydride Dithranol, or anthralin This set index page lists chemical structure articles associated...

Word Count : 58

Deuterated etifoxine

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 537

Etifoxine

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 3481

IARC group 3

Last Update:

Dinitrosopentamethylenetetramine 2,4'-Diphenyldiamine Disperse Yellow 3 Disulfiram Dithranol Doxefazepam Doxylamine succinate Droloxifene Dulcin Electric fields (extremely...

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Translocator protein

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 3181

Olesoxime

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 689

Araroba powder

Last Update:

cause much alarm if administered to a patient whose urine is alkaline. Dithranol and chrysophanic acid are therapeutic substances in araroba powder that...

Word Count : 905

Aquasome

Last Update:

in vivo drug release and targeting. Applications such as delivery of dithranol for the treatment of psoriasis and oral delivery of bromelain for the...

Word Count : 2843

Alpidem

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 4669

Diazepam binding inhibitor

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 970

Nicholas Lowe

Last Update:

Retrieved 21 January 2018. Lowe, N J (28 March 1987). "Phototherapy and dithranol treatment of psoriasis". BMJ. 294 (6575): 839. doi:10.1136/bmj.294.6575...

Word Count : 1366

Emapunil

Last Update:

Agonists Alpidem DAA-1097 DAA-1106 DBI 17-50 fragment Deuterated etifoxine Dithranol (anthralin) Diazepam Diazepam binding inhibitor (DBI) DPA-713 DPA-714...

Word Count : 659

Dihydroxyanthraquinone

Last Update:

PMID 6309924. Kemény, L.; Ruzicka, T.; Braun-Falco, O. (1990). "Dithranol: a review of the mechanism of action in the treatment of psoriasis vulgaris"...

Word Count : 474
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