Disodium aurothiomalate information

Disodium aurothiomalate
Clinical data
Routes of; administration	Intramuscular injection
ATC code	monomer: none;
Pharmacokinetic data
Bioavailability	0%
Excretion	Renal, very slow
Identifiers
CAS Number	monomer: 12244-57-4 ;
PubChem CID	monomer: 71443;
UNII	monomer: E4768ZY6GM;
CompTox Dashboard (EPA)	monomer: DTXSID9048986 ;
ECHA InfoCard	100.151.944
Chemical and physical data
Formula	C4H3AuNa2O4S
Molar mass	390.07 g·mol−1
3D model (JSmol)	monomer: Interactive image; hexamer: Interactive image;
	SMILES monomer: [Na]OC(=O)CC(C(=O)O[Na])S[Au]; ; hexamer: [Na]OC(=O)CC(C(=O)O[Na])S[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au];
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Disodium aurothiomalate is a chemical compound with the formula AuSCH(CO₂Na)CH₂CO₂Na. In conjunction with its monoprotonated derivative, this coordination complex or closely related species are used to treat rheumatoid arthritis, under the tradename Myochrysine.^[1] The thiomalate is racemic in most formulation.

^ Shaw III CF (September 1999). "Gold-based therapeutic agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.

[shaw-1] Shaw III CF (September 1999). "Gold-based therapeutic agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.

Clinical data

Routes of administration	Intramuscular injection
ATC code	monomer: none
Pharmacokinetic data
Bioavailability	0%
Excretion	Renal, very slow
Identifiers
CAS Number	monomer: 12244-57-4^Y
PubChem CID	monomer: 71443
UNII	monomer: E4768ZY6GM
CompTox Dashboard (EPA)	monomer: DTXSID9048986
ECHA InfoCard	100.151.944
Chemical and physical data
Formula	C₄H₃AuNa₂O₄S
Molar mass	390.07 g·mol⁻¹
3D model (JSmol)	monomer: Interactive image hexamer: Interactive image
SMILES monomer: [Na]OC(=O)CC(C(=O)O[Na])S[Au] hexamer: [Na]OC(=O)CC(C(=O)O[Na])S[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au-][S+](C(C(=O)O[Na])C(C(=O)O[Na]))[Au]
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