Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the RNase III family, Dicer cleaves double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short double-stranded RNA fragments called small interfering RNA and microRNA, respectively. These fragments are approximately 20–25 base pairs long with a two-base overhang on the 3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic component Argonaute, which is an endonuclease capable of degrading messenger RNA (mRNA).
^ abcGRCh38: Ensembl release 89: ENSG00000100697 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000041415 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the...
Dice (sg.: die or dice) are small, throwable objects with marked sides that can rest in multiple positions. They are used for generating random values...
Dicing is a culinary knife cut in which the food item is cut into small blocks or dice. This may be done for aesthetic reasons or to create uniformly sized...
A dication is any cation, of general formula X2+, formed by the removal of two electrons from a neutral species. Diatomic dications corresponding to stable...
Dice 10,000 (or 10000, 10,000 Dice, Ten Grand) also Greed, Dix Mille, Reload, 5-Dice is the name of a family dice game played with 6 dice; it is similar...
Although DCL1, also called Endoribonuclease Dicer homolog 1, is named for its homology with the metazoan protein Dicer, its role in miRNA biogenesis is somewhat...
dice, also known as fluffy dice, soft dice, or stuffed dice, are an automotive decoration consisting of two oversized (usually six-sided) plush dice which...
Sicherman dice /ˈsɪkərmən/ are a pair of 6-sided dice with non-standard numbers–one with the sides 1, 2, 2, 3, 3, 4 and the other with the sides 1, 3...
Poker dice are dice which, instead of having number pips, have representations of playing cards upon them. Poker dice have six sides, one each of an Ace...
No Dice is the third studio album by British rock band Badfinger, issued by Apple Records and released on 9 November 1970. Their second album under the...
Dice games are games that use or incorporate one or more dice as their sole or central component, usually as a random device. The following are games...
A dicing saw is a kind of saw which employs a high-speed spindle fitted with an extremely thin diamond blade or diamond wire to dice, cut, or groove semiconductor...
Dice notation (also known as dice algebra, common dice notation, RPG dice notation, and several other titles) is a system to represent different combinations...
which the Dicer-produced initiating or 'primary' siRNAs are used as templates. These 'secondary' siRNAs are structurally distinct from Dicer-produced siRNAs...
Long dice (sometimes oblong or stick dice) are dice, often roughly right prisms or (in the case of barrel dice) antiprisms, designed to land on any of...
The Dice Man is a 1971 novel by American novelist George Cockcroft, writing under the pen name "Luke Rhinehart". The book tells the story of a psychiatrist...
Bar dice is a drinking game played with five dice and a cup. Generally played in a bar, tavern or pub, the game is often used to determine which of the...
The DICE framework or Duration, Integrity, Commitment and Effort framework is a tool originally developed by Perry Keenan, Kathleen Conlon, and Alan Jackson...
Andrew Dice Clay (born Andrew Clay Silverstein; September 29, 1957) is an American stand-up comedian and actor. He rose to prominence in the late 1980s...
singulation method used. A full-cut laser dicer has the ability to cut and separate in a variety of shapes. Materials diced include glass, alumina, silicon, gallium...
The Dynamic Integrated Climate-Economy model, referred to as the DICE model or Dice model, is a neoclassical integrated assessment model developed by 2018...
Dice stacking is a performance art, akin to juggling or sleight-of-hand, in which the performer scoops dice off a flat surface with a dice cup and then...
Dice chess can refer to a number of chess variants in which dice are used to alter gameplay; specifically that the moves available to each player are determined...
known as Mark Dice, is an American YouTuber, right-wing conservative political commentator, author, activist, and conspiracy theorist. Dice is the founder...
"Tumbling Dice" is a song by the English rock band the Rolling Stones. It was released worldwide as the lead single from the band's 1972 double album Exile...
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