Desorption atmospheric pressure photoionization (DAPPI) is an ambient ionization technique for mass spectrometry that uses hot solvent vapor for desorption in conjunction with photoionization. Ambient Ionization techniques allow for direct analysis of samples without pretreatment.[1] The direct analysis technique, such as DAPPI, eliminates the extraction steps seen in most nontraditional samples. DAPPI can be used to analyze bulkier samples, such as, tablets, powders, resins, plants, and tissues. The first step of this technique utilizes a jet of hot solvent vapor.[2] The hot jet thermally desorbs the sample from a surface.[2] The vaporized sample is then ionized by the vacuum ultraviolet light and consequently sampled into a mass spectrometer.[1] DAPPI can detect a range of both polar and non-polar compounds, but is most sensitive when analyzing neutral or non-polar compounds.[3] This technique also offers a selective and soft ionization for highly conjugated compounds.[4]
^Kauppila TJ, Arvola V, Haapala M, Pól J, Aalberg L, Saarela V, Franssila S, Kotiaho T, Kostiainen R (2008). "Direct analysis of illicit drugs by desorption atmospheric pressure photoionization". Rapid Commun. Mass Spectrom. 22 (7): 979–985. doi:10.1002/rcm.3461. PMID 18320545.
^Weston, Daniel J. (2010-03-22). "Ambient ionization mass spectrometry: current understanding of mechanistic theory; analytical performance and application areas". The Analyst. 135 (4): 661–8. Bibcode:2010Ana...135..661W. doi:10.1039/b925579f. ISSN 1364-5528. PMID 20309440.
and 12 Related for: Desorption atmospheric pressure photoionization information
Desorptionatmosphericpressurephotoionization (DAPPI) is an ambient ionization technique for mass spectrometry that uses hot solvent vapor for desorption...
ions that can be sampled into a mass spectrometer. Desorptionatmosphericpressurephotoionization (DAPPI) is a solid-liquid extraction ambient ionization...
that is resonant in the atom or molecule being ionized. Atmosphericpressurephotoionization (APPI) uses a source of photons, usually a vacuum UV (VUV)...
et al., Detection of melamine in milk products by surface desorptionatmosphericpressure chemical ionization mass spectrometry. Anal. Chem., 2009. 81(7):...
through methods such as matrix-assisted laser desorption, electrospray ionization, and atmospheric-pressure chemical ionization. Both solid and liquid samples...
ionized. Radioactive sources, secondary electrospray ionization or photoionization are example methods used to ionize collected vapors. These ions are...
components can be achieved by field desorption ionization and atmosphericpressurephotoionization (APPI). field desorption FT-ICR MS has enabled the identification...
indicates that the smallest dust grains dominate this method of heating. Photoionization When an electron is freed from an atom (typically from absorption of...
fluoride laser Argus laser Asterix IV laser Astrophysical maser Atmospheric-pressure laser ionization Atom interferometer Atom laser Atom probe Atomic...
Global Information