DPP10 information

DPP10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4WJL
Identifiers
Aliases	DPP10, DPL2, DPPY, DPRP-3, DPRP3, dipeptidyl peptidase like 10
External IDs	OMIM: 608209; MGI: 2442409; HomoloGene: 41400; GeneCards: DPP10; OMA:DPP10 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	115,845,780 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	124,773,776 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; Brodmann area 46; ; cingulate gyrus; ; anterior cingulate cortex; ; primary visual cortex; ; amygdala;
	Top expressed in
	substantia nigra; ; piriform cortex; ; prefrontal cortex; ; temporal lobe; ; amygdala; ; primary motor cortex; ; cingulate gyrus; ; lateral septal nucleus; ; lobe of cerebellum; ; medial dorsal nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	potassium channel regulator activity; serine-type peptidase activity; dipeptidyl-peptidase activity; transmembrane transporter binding;
Cellular component	integral component of membrane; plasma membrane; membrane; voltage-gated potassium channel complex;
Biological process	protein localization to plasma membrane; regulation of potassium ion transmembrane transport; proteolysis; positive regulation of protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	57628
	269109
	ENSG00000175497
	ENSMUSG00000036815
	Q8N608
	Q6NXK7
NM_001004360; NM_001178034; NM_001178036; NM_001178037; NM_020868;
	NM_001321905; NM_001321906; NM_001321907; NM_001321908; NM_001321909; NM_001321910; NM_001321911; NM_001321912; NM_001321913; NM_001321914; NM_001399849; NM_001399850; NM_001399851
	NM_199021
NP_001004360; NP_001171505; NP_001171507; NP_001171508; NP_001308834;
	NP_001308835; NP_001308836; NP_001308837; NP_001308838; NP_001308839; NP_001308840; NP_001308841; NP_001308842; NP_001308843; NP_065919
	NP_950186; NP_001393353; NP_001393354; NP_001393355
	Wikidata
View/Edit Human	View/Edit Mouse

Inactive dipeptidyl peptidase 10 is a protein that in humans is encoded by the DPP10 gene.^[5]^[6]^[7] Alternate transcriptional splice variants, encoding different isoforms, have been characterized.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175497 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036815 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
^ Qi SY, Riviere PJ, Trojnar J, Junien JL, Akinsanya KO (Jun 2003). "Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases". Biochem J. 373 (Pt 1): 179–89. doi:10.1042/BJ20021914. PMC 1223468. PMID 12662155.
^ ^a ^b "Entrez Gene: DPP10 dipeptidyl-peptidase 10".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175497 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036815 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10819331-5] Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.

[pmid12662155-6] Qi SY, Riviere PJ, Trojnar J, Junien JL, Akinsanya KO (Jun 2003). "Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases". Biochem J. 373 (Pt 1): 179–89. doi:10.1042/BJ20021914. PMC 1223468. PMID 12662155.

[entrez-7] "Entrez Gene: DPP10 dipeptidyl-peptidase 10".

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