negative regulation of transcription by RNA polymerase II
chromatin organization
nervous system development
histone acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
negative regulation of myeloid progenitor cell differentiation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
5977
19708
Ensembl
ENSG00000133884
ENSMUSG00000024826
UniProt
Q92785
Q61103
RefSeq (mRNA)
NM_006268 NM_001330308
NM_001291078 NM_011262
RefSeq (protein)
NP_001317237 NP_006259 NP_006259.1
NP_001278007 NP_035392
Location (UCSC)
Chr 11: 65.33 – 65.35 Mb
Chr 19: 5.95 – 5.96 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Zinc finger protein ubi-d4 is a protein that in humans is encoded by the DPF2 gene.[5][6]
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000133884 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000024826 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ninkina NN, Mertsalov IB, Kulikova DA, Alimova-Kost MV, Simonova OB, Korochkin LI, Kiselev SL, Buchman VL (Feb 2002). "Cerd4, third member of the d4 gene family: expression and organization of genomic locus". Mamm Genome. 12 (11): 862–6. doi:10.1007/s00335-001-3039-1. PMID 11845289. S2CID 2149578.
^ ab"Entrez Gene: DPF2 D4, zinc and double PHD fingers family 2".
Zinc finger protein ubi-d4 is a protein that in humans is encoded by the DPF2 gene. The protein encoded by this gene is a member of the d4 domain family...