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Craniopagus twins information


Craniopagus twins
Craniopagus twins
SpecialtyNeurosurgery, neuroimaging, medical genetics
Usual onsetIn utero
Diagnostic methodObstetric ultrasonography
Frequency1 in 2.5 million live births

Craniopagus twins are conjoined twins who are fused at the cranium.[1] The union may occur on any portion of the cranium, but does not primarily involve either the face or the foramen magnum; their brains are usually separate, but they may share some brain tissue. Conjoined twins are genetically identical and always share the same sex.[2] The thorax and abdomen are separate and each twin has their own umbilicus and umbilical cord.[3]

The condition is extremely rare, with an incidence of approximately 1 in 2.5 million live births.[3] An estimated 50 craniopagus twins are born around the world every year as of 2021, with only 15 twins surviving beyond the first 30 days of life.[4] Relatively few craniopagus twins survive the perinatal period; approximately 40% of conjoined twins are stillborn and an additional 33% die within the immediate perinatal period, usually from organ abnormalities and failure.[5]

However, 25% of craniopagus twins survive and may be considered for a surgical separation; several such attempts occur annually worldwide.[6] Advances in neuroimaging, neuroanesthesia, and neurosurgery have proven that a successful outcome is possible.[3] Among all conjoined twins, craniopagus twins account for a mere 2% to 6%.[3]

  1. ^ A. B. Todorov; K. L. Cohen; V. Spilotro; E. Landau (1974). "Craniopagus twins" (PDF). Journal of Neurology, Neurosurgery & Psychiatry. 37 (12): 1291–1298. doi:10.1136/jnnp.37.12.1291. PMC 1083642. PMID 4448993. Retrieved 6 September 2021.
  2. ^ Cite error: The named reference mayo was invoked but never defined (see the help page).
  3. ^ a b c d A.E. Goldman-Yassen; J.T. Goodrich; T.S. Miller; J.M. Farinhas (June 2020). "Preoperative Evaluation of Craniopagus Twins: Anatomy, Imaging Techniques, and Surgical Management". American Journal of Neuroradiology. 41 (6): 951–959. doi:10.3174/ajnr.A6571. PMC 7342745. PMID 32439641. Retrieved 6 September 2021.
  4. ^ Isabella Kwai; Myra Noveck (6 September 2021). "Twins Conjoined at the Head Separated in Israel". New York Times. Retrieved 6 September 2021.
  5. ^ Samuel R. Browd; James T. Goodrich; Marion L. Walker (January 2008). "Craniopagus twins". Journal of Neurosurgery: Pediatrics. 1 (1): 1–20. doi:10.3171/PED-08/01/001. PMID 18352797. S2CID 21056359. Retrieved 6 September 2021.
  6. ^ Jen Christensen (24 April 2014). "Conjoined twins: When parents have to make a difficult decision". CNN. Retrieved 2022-02-09.

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