Clazosentan information

Clazosentan
Clinical data
Trade names	Pivlaz
ATC code	C04AX33 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 5-methyl-pyridin-2-sulfonic acid{6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}amide;
CAS Number	180384-56-9;
PubChem CID	6433095;
DrugBank	DB06677;
ChemSpider	4938283;
UNII	3DRR0X4728;
KEGG	D11664;
ChEMBL	ChEMBL109648;
CompTox Dashboard (EPA)	DTXSID60170955 ;
Chemical and physical data
Formula	C25H23N9O6S
Molar mass	577.58 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CN=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=CC(=NC=C3)C4=NNN=N4)OCCO)OC5=CC=CC=C5OC;
	InChI InChI=1S/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34); Key:LFWCJABOXHSRGC-UHFFFAOYSA-N;

Clazosentan (INN, brand name Pivlaz^[1]) is a drug belonging to the class of endothelin receptor antagonists.

^ "Idorsia receives Japanese PMDA approval of Pivlaz" (Press release). Idorsia. 20 January 2022. Retrieved 22 January 2022 – via GlobalNewsWire.

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