Monoclonal antibody
Cirmtuzumab Type ? Source Humanized Target ROR1 Other names UC-961 Legal status
CAS Number 1643432-38-5 Y UNII
Cirmtuzumab (also UC-961 ) is an anti-ROR1 humanised monoclonal antibody.[1] [2]
It is an experimental drug in early-stage clinical trials for various cancers including chronic lymphocytic leukemia (CLL).[3] [4]
^ Choi MY, Widhopf GF, Castro J, Li H, Kidwell RL, Zhang SC, et al. (2015). "Cirmtuzumab (UC-961), a First-in-Class Anti-ROR1 Monoclonal Antibody: Planned Interim Analysis of Initial Phase 1 Cohorts". Blood . 126 (23): 1736. doi:10.1182/blood.V126.23.1736.1736.
^ "Researchers to test novel drug combination against toughest breast cancers". Medical Express. 2018-08-27.
^ Clinical trial number NCT03420183 for "A Study of Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies" at ClinicalTrials.gov
^ "1st Mantle Cell Lymphoma Patient Dosed in Phase 1/2 Trial Testing Cirmtuzumab-Imbruvica Combo". Lymphoma News Today. 2018-05-18.
Last Update: 2023-08-18T09:07:05Z
Cirmtuzumab (also UC-961) is an anti-ROR1 humanised monoclonal antibody. It is an experimental drug in early-stage clinical trials for various cancers...
Word Count : 135
Last Update: 2023-09-19T07:02:10Z
Thomas Kipps, discoverer of ROR1, and contributed to the development of cirmtuzumab Don W. Cleveland Marilyn Farquhar Napoleone Ferrara Quyen T. Nguyen "UC...
Word Count : 329
Last Update: 2024-01-20T22:02:48Z
discovery of a potential treatment for chronic lymphomatic leukemia called Cirmtuzumab . The health system coordinates its activities closely with the UC San...
Word Count : 2631
Last Update: 2020-10-19T22:00:31Z
mertansine§ Brontictuzumab§ Cantuzumab mertansine§ Cantuzumab ravtansine§ Cirmtuzumab Citatuzumab bogatox§ Clivatuzumab tetraxetan Cofetuzumab pelidotin Dacetuzumab§...
Word Count : 368
Last Update: 2022-04-22T11:41:06Z
mertansine§ Brontictuzumab§ Cantuzumab mertansine§ Cantuzumab ravtansine§ Cirmtuzumab Citatuzumab bogatox§ Clivatuzumab tetraxetan Cofetuzumab pelidotin Dacetuzumab§...
Word Count : 241