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Cinoxate information


Cinoxate[1]
Ball-and-stick model of the cinoxate molecule
Space-filling model of the cinoxate molecule
Names
Preferred IUPAC name
2-Ethoxyethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
Other names
2-Ethoxyethyl p-methoxycinnamate
Identifiers
CAS Number
  • 104-28-9 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL2104045 ☒N
ChemSpider
  • 4523729 checkY
ECHA InfoCard 100.002.901 Edit this at Wikidata
KEGG
  • D03512 checkY
PubChem CID
  • 5373773
UNII
  • 5437O7N5BH checkY
CompTox Dashboard (EPA)
  • DTXSID101167513 DTXSID2025264, DTXSID101167513 Edit this at Wikidata
InChI
  • InChI=1S/C14H18O4/c1-3-17-10-11-18-14(15)9-6-12-4-7-13(16-2)8-5-12/h4-9H,3,10-11H2,1-2H3/b9-6+ checkY
    Key: CMDKPGRTAQVGFQ-RMKNXTFCSA-N checkY
  • InChI=1/C14H18O4/c1-3-17-10-11-18-14(15)9-6-12-4-7-13(16-2)8-5-12/h4-9H,3,10-11H2,1-2H3/b9-6+
    Key: CMDKPGRTAQVGFQ-RMKNXTFCBV
SMILES
  • O=C(OCCOCC)\C=C\c1ccc(OC)cc1
Properties
Chemical formula
C14H18O4
Molar mass 250.294 g·mol−1
Density 1.102 g/cm3
Melting point −25 °C (−13 °F; 248 K)
Boiling point 184 to 187 °C (363 to 369 °F; 457 to 460 K) at 2 mmHg
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Cinoxate is an organic compound used as an ingredient in some types of sunscreens. It is an ester formed from methoxycinnamic acid and 2-ethoxyethanol. It is a slightly yellow viscous liquid that is insoluble in water, but miscible with alcohols, esters, and vegetable oils.

It was approved as UV filter in the USA by the FDA in 1961, but it is not commonly used in cosmetic formulations anymore.[2]

  1. ^ Merck Index, 11th Edition, 2312.
  2. ^ Pantelic, Molly N.; Wong, Nikita; Kwa, Michael; Lim, Henry W. (24 February 2023). "Ultraviolet filters in the United States and European Union: A review of safety and implications for the future of US sunscreens". Journal of the American Academy of Dermatology. 88 (3): 632–646. doi:10.1016/j.jaad.2022.11.039.

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Cinoxate is an organic compound used as an ingredient in some types of sunscreens. It is an ester formed from methoxycinnamic acid and 2-ethoxyethanol...

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Octyl methoxycinnamate

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four stereoisomers: Amiloxate, a chemically related sunscreening agent Cinoxate, another cinnamic acid based sunscreen ingredient Avobenzone – UV-A protectant...

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Sunscreen

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4% (USA, AUS) 8% (EU) 3% (JP) EU, USA, AUS, JP Genotoxic in bacteria X Cinoxate 2-Ethoxyethyl p-methoxycinnamate 3% (USA) 6% (AUS) USA, AUS X X Dioxybenzone...

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C14H18O4

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The molecular formula C14H18O4 (molar mass: 250.29 g/mol) may refer to : Cinoxate, an ingredient in some types of sunscreens Trolox, water-soluble derivative...

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No Ordinary Family

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leap over tall buildings (or jump a quarter-mile). When in contact with cinoxate, his powers fail. His weakness lies in finesse and agility. Julie Benz...

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