Chronic paroxysmal hemicrania (CPH) is a severe debilitating unilateral headache usually affecting the area around the eye. It normally consists of multiple severe, yet short, headache attacks affecting only one side of the cranium. Retrospective surveys indicated that paroxysmal hemicrania was more common in women.[1][2] However, subsequent prospective research showed an equal prevalence between females and males, with a ratio close to 1:1.[3] Unlike in migraine, it has no neurological symptoms associated with it. CPH headaches are treated through the use of non-steroidal anti-inflammatory drugs, with indomethacin found to be especially effective in eliminating symptoms.
Paroxysmal hemicrania is classified by the characteristic (high) frequency and (short) duration of attacks experienced by patients that is somewhat similar to cluster headaches, despite some important differences explained below.[4] Episodic paroxysmal hemicrania attacks occur at least twice a year and last anywhere from seven days to a year with pain free periods of a month or longer separating them. Chronic paroxysmal hemicrania attacks occur over the course of more than a year without remission or with remissions lasting less than a month.[5]
^Antonaci, Fabio; Sjaastad, Ottar (November 1989). "Chronic Paroxysmal Hemicrania (CPH): A Review of the Clinical Manifestations". Headache: The Journal of Head and Face Pain. 29 (10): 648–656. doi:10.1111/j.1526-4610.1989.hed2910648.x. ISSN 0017-8748. PMID 2693408.
^Boes, Christopher J.; Dodick, David W. (September 2002). "Refining the clinical spectrum of chronic paroxysmal hemicrania: a review of 74 patients". Headache. 42 (8): 699–708. doi:10.1046/j.1526-4610.2002.02171.x. ISSN 0017-8748. PMID 12390632.
^Cittadini, Elisabetta; Matharu, Manjit S.; Goadsby, Peter J. (April 2008). "Paroxysmal hemicrania: a prospective clinical study of 31 cases". Brain: A Journal of Neurology. 131 (Pt 4): 1142–1155. doi:10.1093/brain/awn010. ISSN 1460-2156. PMID 18252775.
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^Goadsby, Peter J., Stephen D. Silberstein, and David Dodick. "Chronic Paroxysmal Hemicrania". Chronic Daily Headache for Clinicians. Hamilton, Ont.: BC Decker, 2005. N. pag. Print.
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