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Chloromethyl methyl ether information


Chloromethyl methyl ether[1]
Skeletal formula of chloromethyl methyl ether
Ball-and-stick model of the chloromethyl methyl ether molecule
Names
Preferred IUPAC name
Chloro(methoxy)methane
Other names
MOM-Cl, CMME, MCD, Chlorodimethyl ether, Chloromethoxymethane, Dimethylchloroether, Methylchloromethyl ether
Identifiers
CAS Number
  • 107-30-2 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 13852893 ☒N
ECHA InfoCard 100.003.165 Edit this at Wikidata
EC Number
  • 203-480-1
KEGG
  • C19160 ☒N
PubChem CID
  • 7864
RTECS number
  • KN6650000
UNII
  • 334G5B96VG ☒N
UN number 1239
CompTox Dashboard (EPA)
  • DTXSID6020307 Edit this at Wikidata
InChI
  • InChI=1S/C2H5ClO/c1-4-2-3/h2H2,1H3 ☒N
    Key: XJUZRXYOEPSWMB-UHFFFAOYSA-N ☒N
  • InChI=1/C2H5ClO/c1-4-2-3/h2H2,1H3
    Key: XJUZRXYOEPSWMB-UHFFFAOYAK
SMILES
  • COCCl
Properties
Chemical formula
C2H5ClO
Molar mass 80.51 g·mol−1
Appearance Colorless liquid
Odor Irritating and acrid
Density 1.06 g/mL
Melting point −103.5 °C (−154.3 °F; 169.7 K)
Boiling point 55–57 °C (131–135 °F; 328–330 K)
Solubility in water
reacts
Solubility Soluble in alcohol and diethylether
Vapor pressure 192 mmHg (21°C)[2]
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Carcinogen & Irritant
GHS labelling:
Pictograms
GHS02: FlammableGHS07: Exclamation markGHS08: Health hazard
Signal word
Danger
Hazard statements
H225, H302, H312, H319, H332, H350
Precautionary statements
P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P322, P330, P337+P313, P363, P370+P378, P403+P235, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 3: Liquids and solids that can be ignited under almost all ambient temperature conditions. Flash point between 23 and 38 °C (73 and 100 °F). E.g. gasolineInstability 2: Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water. E.g. white phosphorusSpecial hazards (white): no code
3
3
2
Flash point 0 °C (32 °F; 273 K) (open cup)[2]
NIOSH (US health exposure limits):
PEL (Permissible)
OSHA-Regulated Carcinogen, no PEL[2]
REL (Recommended)
Carcinogenic[2]
IDLH (Immediate danger)
N.D.[2]
Safety data sheet (SDS) Safety Data Sheet Archived
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Chloromethyl methyl ether (CMME) is a compound with formula CH3OCH2Cl. A colorless liquid, it is a chloroalkyl ether. It is used as an alkylating agent. In organic synthesis, it is used for introducing the methoxymethyl ether (MOM) protecting group,[3] and is thus often called MOM-Cl or MOM chloride. It also finds application as a chloromethylating agent in some variants of the Blanc chloromethylation.[4]

  1. ^ Sigma-Aldrich
  2. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0129". National Institute for Occupational Safety and Health (NIOSH).
  3. ^ Protective Groups in Organic Synthesis, T. W. Greene and P. G. M. Green, 3rd Edition, pages 27-33. ISBN 0-471-16019-9
  4. ^ Wuts, Peter G. M. (2001). "Chloromethyl Methyl Ether". Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rc118. ISBN 0471936235.

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C2H5ClO

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