Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Cerberin is a type of cardiac glycoside, a steroidal class found in the seeds of the dicotyledonous angiosperm genus Cerbera; including the suicide tree (Cerbera odollam) and the sea mango (Cerbera manghas). As a cardiac glycoside, cerberin disrupts the function of the heart by blocking its sodium and potassium ATPase.[2] Cerberin can be used as a treatment for heart failure and arrhythmia.[3]
Overconsumption of cerberin results in poisoning. Symptoms include nausea, vomiting, and bradycardia, often leading to death.[4] Cerberin containing plants such as Cerbera odollam have historically been used for suicide and homicide in their growth regions due to their high toxicity.
^"cerberin | 25633-33-4". ChemicalBook. Retrieved 5 May 2024.
^Botelho, Ana Flávia M.; Pierezan, Felipe; Soto-Blanco, Benito; Melo, Marília Martins (February 2019). "A review of cardiac glycosides: Structure, toxicokinetics, clinical signs, diagnosis and antineoplastic potential". Toxicon. 158: 63–68. doi:10.1016/j.toxicon.2018.11.429. PMID 30529380.
^"Cardiac glycoside overdose: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 5 May 2024.
^Gaillard, Yvan; Krishnamoorthy, Ananthasankaran; Bevalot, Fabien (December 2004). "Cerbera odollam: a 'suicide tree' and cause of death in the state of Kerala, India". Journal of Ethnopharmacology. 95 (2–3): 123–126. doi:10.1016/j.jep.2004.08.004. PMID 15507323.
Cerberin is a type of cardiac glycoside, a steroidal class found in the seeds of the dicotyledonous angiosperm genus Cerbera; including the suicide tree...
toxic cardiac glycoside cerberin, as well as tanghinin, deactyltanghin, and neriifolin. Only the mechanism of action for cerberin has been extensively studied...
bears a fruit known as othalanga whose seeds yield a potent poison called cerberin that has been used for trials by ordeal, suicide, and poisonings. It is...
produces seeds that contain highly toxic cardiac glycosides including cerberin and tanghinin. The tradition of the tangena ordeal, dates to at least the...
wallflower) and other Erysimum species Cerbera odollam (suicide tree): cerberin Periploca sepium: periplocin some species of Chrysolina beetles, including...
cephalathin. Cerbera odollam suicide tree Apocynaceae The seeds contain cerberin, a potent toxin related to digoxin. The poison blocks the calcium ion channels...
Greek mythology, because all the species are poisonous — they contain cerberin, a cardiac glycoside, a substance that blocks electric impulses in the...
plant are toxic to humans. Cerbera species contain the cardiac glycoside cerberin, and if eaten will result in nausea, vomiting, abdominal pain, and potentially...
C32H48O9 (molar mass: 576.72 g/mol, exact mass: 576.3298 u) may refer to: Cerberin, a cardiac glycoside Oleandrin, a cardiac glycoside This set index page...