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Caries vaccine information


A caries vaccine is a vaccine to prevent and protect against tooth decay.[1] Streptococcus mutans (S. mutans) has been identified as the major etiological agent of human dental caries. The development of a vaccine for tooth decay has been under investigation since the 1970s. In 1972, a caries vaccine was said to be in animal testing in England, and that it would have begun human testing soon.[2] However, intrinsic difficulties in developing it, coupled with lack of strong economic interests, are the reasons why still no such vaccine is commercially available today.[citation needed] Several types of vaccines are being developed at research centres, with some kind of caries vaccines being considered to diminish or prevent dental caries' impact on young people.[3]

  1. ^ "Panel on Caries Vaccine". National Institute of Dental and Craniofacial Research of the National Institute of Health. January 28, 2003. Archived from the original on 2011-09-29. Retrieved 14 April 2008.
  2. ^ Bowen, W.H. (December 1972). "Dental caries". Archives of Disease in Childhood. 47 (256): 849–53. doi:10.1136/adc.47.256.849. PMC 1648396. PMID 4567073.
  3. ^ Richie, Chhabra; Karan, Rajpal (Jan 2016). "Caries vaccine: A boom for public health". Annals of Tropical Medicine & Public Health. 9 (1): 1–3. doi:10.4103/1755-6783.168715. S2CID 57200550.

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