According to the cardiocentric hypothesis, the heart has a profound influence on human emotions, cognition, and awareness. This notion may be traced back to ancient civilizations such as Egypt and Greece, where the heart was regarded not only as a physical organ but also as a repository of emotions and wisdom.[1] Aristotle, a well-known Greek philosopher in this field, contributed to the notion by thinking the heart to be the centre of both emotions and intellect. He believed that the heart was the center of the psycho-physiological system and that it was responsible for controlling sensation, thought, and body movement. He also observed that the heart was the origin of the veins in the body and that the existence of pneuma in the heart was to function as a messenger, traveling through blood vessels to produce sensation.[2] This point of view remained throughout history, spanning the Middle Ages and Renaissance, influencing medical and intellectual debate.[1]
An opposing theory called "cephalocentrism", which proposed that the brain played the dominant role in controlling the body, was first introduced by Pythagoras in 550 BC, who argued that the soul resides in the brain and is immortal.[3] His statements were supported by Plato, Hippocrates, and Galen of Pergamon. Plato believed that the body is a "prison" of the mind and soul and that in death the mind and soul become separated from the body, meaning that neither one of them could die.[4]