CXorf38 Isoform 1 information

CXorf38
Identifiers
Aliases	CXorf38, chromosome X open reading frame 38, CXorf38 Isoform 1
External IDs	MGI: 1916405; HomoloGene: 17013; GeneCards: CXorf38; OMA:CXorf38 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	40,647,561 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	12,539,907 bp
RNA expression pattern
	Top expressed in
	monocyte; ; pancreatic epithelial cell; ; blood; ; palpebral conjunctiva; ; secondary oocyte; ; amniotic fluid; ; pancreatic ductal cell; ; lymph node; ; thymus; ; spleen;
	Top expressed in
	corneal stroma; ; interventricular septum; ; plantaris muscle; ; extensor digitorum longus muscle; ; ankle joint; ; seminal vesicula; ; parotid gland; ; sciatic nerve; ; ascending aorta; ; lacrimal gland;
	More reference expression data
	n/a
Orthologs
	159013
	69155
	ENSG00000185753
	ENSMUSG00000044148
	Q8TB03
	Q8C5K5
	NM_144970; NM_001330455
	NM_175141
	NP_001317384; NP_659407
	NP_780350
	Wikidata
View/Edit Human	View/Edit Mouse

Chromosome X Open Reading Frame 38 (CXorf38) is a protein which, in humans, is encoded by the CXorf38 gene.^[5] CXorf38 appears in multiple studies regarding the escape of X chromosome inactivation (see Clinical Significance).^[6]^[7]^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185753 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044148 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ NCBI (National Center for Biotechnology Information) Protein entry on Uncharacterized Protein CXorf38 Isoform 1 [1]
^ Wen G, Ramser J, Taudien S, Gausmann U, Blechschmidt K, Frankish A, et al. (December 2005). "Validation of mRNA/EST-based gene predictions in human Xp11.4 revealed differences to the organization of the orthologous mouse locus". Mammalian Genome. 16 (12): 934–41. doi:10.1007/s00335-005-0090-3. PMID 16341673. S2CID 38772314.
^ Zhang Y, Castillo-Morales A, Jiang M, Zhu Y, Hu L, Urrutia AO, et al. (December 2013). "Genes that escape X-inactivation in humans have high intraspecific variability in expression, are associated with mental impairment but are not slow evolving". Molecular Biology and Evolution. 30 (12): 2588–601. doi:10.1093/molbev/mst148. PMC 3840307. PMID 24023392.
^ Luijk R, Wu H, Ward-Caviness CK, Hannon E, Carnero-Montoro E, Min JL, et al. (September 2018). "Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation". Nature Communications. 9 (1): 3738. Bibcode:2018NatCo...9.3738L. doi:10.1038/s41467-018-05714-3. PMC 6138682. PMID 30218040.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185753 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044148 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:1-5] NCBI (National Center for Biotechnology Information) Protein entry on Uncharacterized Protein CXorf38 Isoform 1 [1]

[:2-6] Wen G, Ramser J, Taudien S, Gausmann U, Blechschmidt K, Frankish A, et al. (December 2005). "Validation of mRNA/EST-based gene predictions in human Xp11.4 revealed differences to the organization of the orthologous mouse locus". Mammalian Genome. 16 (12): 934–41. doi:10.1007/s00335-005-0090-3. PMID 16341673. S2CID 38772314.

[:3-7] Zhang Y, Castillo-Morales A, Jiang M, Zhu Y, Hu L, Urrutia AO, et al. (December 2013). "Genes that escape X-inactivation in humans have high intraspecific variability in expression, are associated with mental impairment but are not slow evolving". Molecular Biology and Evolution. 30 (12): 2588–601. doi:10.1093/molbev/mst148. PMC 3840307. PMID 24023392.

[:4-8] Luijk R, Wu H, Ward-Caviness CK, Hannon E, Carnero-Montoro E, Min JL, et al. (September 2018). "Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation". Nature Communications. 9 (1): 3738. Bibcode:2018NatCo...9.3738L. doi:10.1038/s41467-018-05714-3. PMC 6138682. PMID 30218040.