RNA polymerase II CTD heptapeptide repeat phosphatase activity
Cellular component
extracellular exosome
nucleus
Biological process
negative regulation of G1/S transition of mitotic cell cycle
negative regulation of protein phosphorylation
dephosphorylation
protein dephosphorylation
regulation of transcription by RNA polymerase II
biological process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
10217
69274
Ensembl
ENSG00000144677
ENSMUSG00000047409
UniProt
O15194
P58465
RefSeq (mRNA)
NM_005808 NM_001008392
NM_133710
RefSeq (protein)
NP_001008393 NP_005799
NP_598471
Location (UCSC)
Chr 3: 37.86 – 37.98 Mb
Chr 9: 118.76 – 118.87 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
CTD small phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000144677 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000047409 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ishikawa S, Kai M, Tamari M, Takei Y, Takeuchi K, Bandou H, Yamane Y, Ogawa M, Nakamura Y (Aug 1997). "Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line". DNA Res. 4 (1): 35–43. doi:10.1093/dnares/4.1.35. PMID 9179494.
^Protopopov A, Kashuba V, Zabarovska VI, Muravenko OV, Lerman MI, Klein G, Zabarovsky ER (Jan 2003). "An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies". Cancer Res. 63 (2): 404–12. PMID 12543795.
^"Entrez Gene: CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like".
phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene. CTDSPL has been shown to interact with SNAI1. GRCh38: Ensembl release 89:...
cancer before chemotherapy treatment. SNAI1 has been shown to interact with CTDSPL, CTDSP1 and CTDSP2. Snail1 affects cell polarity by interacting with members...