negative regulation of cysteine-type endopeptidase activity
negative regulation of endopeptidase activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
128821
13013
Ensembl
ENSG00000101435
ENSMUSG00000027445
UniProt
Q9H4G1
Q9Z0H6
RefSeq (mRNA)
NM_080610
NM_009979
RefSeq (protein)
NP_542177
NP_034109
Location (UCSC)
Chr 20: 23.56 – 23.57 Mb
Chr 2: 148.68 – 148.68 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Cystatin-9-like is a protein that in humans is encoded by the CST9L gene.[5]
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to mouse cystatin 9. Based on its testis-specific expression, it is likely to have a role in tissue reorganization during early testis development.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000101435 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000027445 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Cystatin-9-like is a protein that in humans is encoded by the CST9L gene. The cystatin superfamily encompasses proteins that contain multiple cystatin-like...