dentate gyrus of hippocampal formation granule cell
entorhinal cortex
perirhinal cortex
hippocampus proper
anterior amygdaloid area
Region I of hippocampus proper
facial motor nucleus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
calcium ion binding
transporter activity
phosphatidylserine binding
protein binding
calcium-dependent phospholipid binding
Cellular component
cytoplasm
endosome
perikaryon
cell projection
membrane
clathrin-coated endocytic vesicle
plasma membrane
axon
dendrite
extracellular exosome
cytoplasmic vesicle
clathrin-coated vesicle
Biological process
cellular response to calcium ion
cell differentiation
lipid metabolism
nervous system development
glycerophospholipid biosynthetic process
positive regulation of dendrite extension
vesicle-mediated transport
chemical synaptic transmission
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
9362
12891
Ensembl
ENSG00000100884
ENSMUSG00000022212
UniProt
O95741
Q9Z140
RefSeq (mRNA)
NM_001280558 NM_006032
NM_001136057 NM_001146183 NM_009947 NM_001360193
RefSeq (protein)
NP_001267487 NP_006023
NP_001129529 NP_001139655 NP_034077 NP_001347122
Location (UCSC)
Chr 14: 24.07 – 24.08 Mb
Chr 14: 55.75 – 55.75 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Copine-6 is a protein that in humans is encoded by the CPNE6 gene.[5][6]
This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000100884 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000022212 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Nakayama T, Yaoi T, Yasui M, Kuwajima G (Jul 1998). "N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression". FEBS Lett. 428 (1–2): 80–4. doi:10.1016/S0014-5793(98)00497-9. PMID 9645480. S2CID 27969998.
Copine-6 is a protein that in humans is encoded by the CPNE6 gene. This gene encodes a brain-specific member of the copine family, which is composed of...
the group of human proteins that includes members such as CPNE1, CPNE4, CPNE6, and CPNE8. These are highly conserved, calcium-dependent membrane proteins...