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CLIP4 information


CLIP4 protein predicted tertiary structure. Taken from PhyreRisk.[1]
CLIP4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCLIP4, RSNL2, CAP-Gly domain containing linker protein family member 4
External IDsMGI: 1919100; HomoloGene: 11662; GeneCards: CLIP4; OMA:CLIP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001287527
NM_001287528
NM_024692

NM_001271483
NM_001271484
NM_030179
NM_175378

RefSeq (protein)

NP_001274456
NP_001274457
NP_078968

NP_001258412
NP_001258413
NP_084455
NP_780587

Location (UCSC)Chr 2: 29.1 – 29.2 MbChr 17: 72.08 – 72.17 Mb
PubMed search[4][5]
Wikidata
View/Edit HumanView/Edit Mouse

CAP-Gly Domain Containing Linker Protein Family Member 4 is a protein that in humans is encoded by the CLIP4 gene.[6] In terms of conserved domains, the CLIP4 gene contains primarily ankyrin repeats and the eponymous CAP-Gly domains.[6] The structure of the CLIP4 protein is largely made up of coil, with alpha helices dominating the rest of the protein.[7] CLIP4 mRNA expression occurs largely in the adrenal cortex and atrioventricular node.[8] The literature encompassing CLIP4's conserved domains and paralogs points toward microtubule regulation as a possible function of CLIP4.

  1. ^ "PhyreRisk". phyrerisk.bc.ic.ac.uk. Retrieved 2020-05-03.
  2. ^ a b c GRCh38: Ensembl release 89: ENSG00000115295 – Ensembl, May 2017
  3. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024059 – Ensembl, May 2017
  4. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  6. ^ a b "CLIP4 CAP-Gly domain containing linker protein family member 4 [Homo sapiens (human)] - Gene - NCBI". ncbi.nlm.nih.gov. Retrieved 2020-05-01.
  7. ^ "CFSSP: Chou & Fasman Secondary Structure Prediction Server". biogem.org. Retrieved 2020-05-03.
  8. ^ Cite error: The named reference :5 was invoked but never defined (see the help page).

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