CLEC16A information

CLEC16A
Identifiers
Aliases	CLEC16A, Gop-1, KIAA0350, C-type lectin domain family 16 member A, C-type lectin domain containing 16A
External IDs	OMIM: 611303 MGI: 1921624 HomoloGene: 71019 GeneCards: CLEC16A
Gene location (Human)
Chr.	Chromosome 16 (human)
End	11,182,186 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	10,562,742 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Brodmann area 10; ; anterior pituitary; ; gastrocnemius muscle; ; stromal cell of endometrium; ; right lobe of liver; ; bone marrow cells; ; cingulate gyrus; ; upper lobe of left lung; ; skin of abdomen;
	Top expressed in
	superior frontal gyrus; ; medial geniculate nucleus; ; cerebellar cortex; ; subiculum; ; inferior colliculus; ; primary motor cortex; ; lateral geniculate nucleus; ; knee joint; ; superior colliculus; ; medial dorsal nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	lysosomal membrane; endosome; lysosome; endosome membrane; membrane; endolysosome membrane; Golgi apparatus; cytosol; vesicle; late endosome; integral component of membrane;
Biological process	autophagy; positive regulation of autophagosome maturation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of mitophagy; cellular response to starvation; negative regulation of autophagosome maturation; positive regulation of TORC1 signaling; negative regulation of macroautophagy by TORC1 signaling; endosome to lysosome transport; endosomal transport;
	Sources:Amigo / QuickGO
Orthologs
	23274
	74374
	ENSG00000038532
	ENSMUSG00000068663
	Q2KHT3
	Q80U30
	NM_001243403; NM_015226
	NM_001204229; NM_177562
	NP_001230332; NP_056041
	NP_001191158; NP_808230
	Wikidata
View/Edit Human	View/Edit Mouse

C-type lectin domain family 16, also known as CLEC16A, is a protein that in humans is encoded by the CLEC16A gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000038532 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068663 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: C-type lectin domain family 16".
^ Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (April 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
^ Hakonarson H, Grant SF, Bradfield JP, Marchand L, Kim CE, Glessner JT, Grabs R, Casalunovo T, Taback SP, Frackelton EC, Lawson ML, Robinson LJ, Skraban R, Lu Y, Chiavacci RM, Stanley CA, Kirsch SE, Rappaport EF, Orange JS, Monos DS, Devoto M, Qu HQ, Polychronakos C (August 2007). "A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene". Nature. 448 (7153): 591–4. Bibcode:2007Natur.448..591H. doi:10.1038/nature06010. PMID 17632545. S2CID 4426917.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000038532 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068663 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: C-type lectin domain family 16".

[pmid9205841-6] Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (April 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.

[pmid17632545-7] Hakonarson H, Grant SF, Bradfield JP, Marchand L, Kim CE, Glessner JT, Grabs R, Casalunovo T, Taback SP, Frackelton EC, Lawson ML, Robinson LJ, Skraban R, Lu Y, Chiavacci RM, Stanley CA, Kirsch SE, Rappaport EF, Orange JS, Monos DS, Devoto M, Qu HQ, Polychronakos C (August 2007). "A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene". Nature. 448 (7153): 591–4. Bibcode:2007Natur.448..591H. doi:10.1038/nature06010. PMID 17632545. S2CID 4426917.