calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
viral process
cell-cell junction organization
viral entry into host cell
tight junction organization
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
9080
56863
Ensembl
ENSG00000213937
ENSMUSG00000066720
UniProt
O95484
Q9Z0S7
RefSeq (mRNA)
NM_020982
NM_020293
RefSeq (protein)
NP_066192
NP_064689
Location (UCSC)
Chr 16: 3.01 – 3.01 Mb
Chr 17: 23.9 – 23.9 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Claudin-9 is a protein that in humans is encoded by the CLDN9 gene.[5][6][7] It belongs to the group of claudins.
This gene is expressed in the inner ear, olfactory epithelium, and anterior pituitary gland [8] and is involved in hearing.[9][10][11]
^ abcGRCh38: Ensembl release 89: ENSG00000213937 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000066720 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Peacock RE, Keen TJ, Inglehearn CF (Mar 1998). "Analysis of a human gene homologous to rat ventral prostate.1 protein". Genomics. 46 (3): 443–9. doi:10.1006/geno.1997.5033. PMID 9441748.
^Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T (Mar 2008). "The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus". J Virol. 82 (7): 3555–60. doi:10.1128/JVI.01977-07. PMC 2268462. PMID 18234789.
^"Entrez Gene: CLDN9 claudin 9".
^Higashi AY, Higashi T, Furuse K, Ozeki K, Furuse M, Chiba H (Nov 2021). "Claudin-9 constitutes tight junctions of folliclo-stellate cells in the anterior pituitary gland". Scientific Reports. 11 (1): 21642. Bibcode:2021NatSR..1121642H. doi:10.1038/s41598-021-01004-z. PMC 8568902. PMID 34737342.
^Gene discovery reveals a critical protein's function in hearing
^Nakano Y, Kim SH, Kim HM, Sanneman JD, Zhang Y, Smith RJ, Marcus DC, Wangemann P, Nessler RA, Bánfi B (Aug 2009). "A claudin-9-based ion permeability barrier is essential for hearing". PLOS Genetics. 5 (8): e1000610. doi:10.1371/journal.pgen.1000610. PMC 2720454. PMID 19696885.
^Sineni CJ, Yildirim-Baylan M, Guo S, Camarena V, Wang G, Tokgoz-Yilmaz S, Duman D, Bademci G, Tekin M (Oct 2019). "A truncating CLDN9 variant if associated with autosomal recessive nonsyndromic hearing loss". Human Genetics. 138 (10): 1071–1075. doi:10.1007/s00439-019-02037-1. PMC 6745279. PMID 31175426.
Claudin-9 is a protein that in humans is encoded by the CLDN9 gene. It belongs to the group of claudins. This gene is expressed in the inner ear, olfactory...