Protein-coding gene in the species Homo sapiens
CLDN12 Identifiers Aliases CLDN12 , claudin 12External IDs OMIM: 611232; MGI: 1929288; HomoloGene: 40809; GeneCards: CLDN12; OMA:CLDN12 - orthologs Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.13 Start 90,383,721 bp[1] End 90,513,402 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 A1 Start 5,539,537 bp[2] End 5,564,958 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte islet of Langerhans pancreatic epithelial cell cartilage tissue mucosa of sigmoid colon right lobe of liver rectum pituitary gland anterior pituitary myocardium of left ventricle
Top expressed in otolith organ utricle interventricular septum retinal pigment epithelium ascending aorta supraoptic nucleus ciliary body primitive streak aortic valve epithelium of lens
More reference expression data
BioGPS
Gene ontology Molecular function
structural molecule activity
identical protein binding
protein binding Cellular component
integral component of membrane
cell junction
lateral plasma membrane
membrane
cell periphery
bicellular tight junction
plasma membrane Biological process
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_012129
NM_001193659
RefSeq (protein) NP_001172001
NP_001180588
Location (UCSC) Chr 7: 90.38 – 90.51 Mb Chr 5: 5.54 – 5.56 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Claudin-12 is a protein that in humans is encoded by the CLDN12 gene.[5] It belongs to the group of claudins.
^ a b c GRCh38: Ensembl release 89: ENSG00000157224 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046798 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Entrez Gene: CLDN12 claudin 12".
Last Update: 2022-10-13T14:00:28Z
Claudin-12 is a protein that in humans is encoded by the CLDN12 gene. It belongs to the group of claudins. GRCh38: Ensembl release 89: ENSG00000157224...
Word Count : 694
Last Update: 2024-02-10T07:26:49Z
CLDN2, CLDN3, CLDN4, CLDN5, CLDN6, CLDN7, CLDN8, CLDN9, CLDN10, CLDN11, CLDN12 , CLDN13, CLDN14, CLDN15, CLDN16, CLDN17, CLDN18, CLDN19, CLDN20, CLDN21...
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