CHMP1B information

CHMP1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EAB, 4TXQ, 4TXR, 3JC1
Identifiers
Aliases	CHMP1B, C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2, charged multivesicular body protein 1B
External IDs	OMIM: 606486; MGI: 1914314; HomoloGene: 41374; GeneCards: CHMP1B; OMA:CHMP1B - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	11,854,444 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	67,340,960 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; beta cell; ; tibialis anterior muscle; ; muscle of thigh; ; glutes; ; mucosa of sigmoid colon; ; popliteal artery; ; tibial arteries; ; biceps brachii; ; monocyte;
	Top expressed in
	transitional epithelium of urinary bladder; ; left colon; ; conjunctival fornix; ; decidua; ; medial ganglionic eminence; ; blood; ; granulocyte; ; thymus; ; duodenum; ; jejunum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein domain specific binding; protein binding; identical protein binding;
Cellular component	cytoplasm; ESCRT III complex; cytosol; endosome; late endosome membrane; membrane; membrane coat; endosome membrane; extracellular exosome; nucleus; midbody; multivesicular body;
Biological process	regulation of centrosome duplication; nucleus organization; establishment of protein localization; multivesicular body assembly; regulation of mitotic spindle assembly; cell division; protein transport; cell cycle; septum digestion after cytokinesis; mitotic metaphase plate congression; vacuolar transport; ESCRT III complex disassembly; transport; viral budding via host ESCRT complex; endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; midbody abscission;
	Sources:Amigo / QuickGO
Orthologs
	57132
	67064
	ENSG00000255112
	ENSMUSG00000109901
	Q7LBR1
	Q99LU0
	NM_020412
	NM_024190
	NP_065145
	NP_077152
	Wikidata
View/Edit Human	View/Edit Mouse

Charged multivesicular body protein 1b is a protein that in humans is encoded by the CHMP1B gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000255112 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000109901 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Reid E, Connell J, Edwards TL, Duley S, Brown SE, Sanderson CM (Dec 2004). "The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B". Hum Mol Genet. 14 (1): 19–38. doi:10.1093/hmg/ddi003. PMID 15537668.
^ "Entrez Gene: CHMP1B chromatin modifying protein 1B".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000255112 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000109901 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15537668-5] Reid E, Connell J, Edwards TL, Duley S, Brown SE, Sanderson CM (Dec 2004). "The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B". Hum Mol Genet. 14 (1): 19–38. doi:10.1093/hmg/ddi003. PMID 15537668.

[entrez-6] "Entrez Gene: CHMP1B chromatin modifying protein 1B".