CFAP157, C9orf117, cilia and flagella associated protein 157
External IDs
MGI: 2447809 HomoloGene: 53056 GeneCards: CFAP157
Gene location (Mouse)
Chr.
Chromosome 2 (mouse)[1]
Band
2|2 B
Start
32,667,393 bp[1]
End
32,674,440 bp[1]
RNA expression pattern
Bgee
Human
Mouse (ortholog)
Top expressed in
right uterine tube
bronchial epithelial cell
left uterine tube
sperm
right lung
anterior pituitary
canal of the cervix
trachea
pancreatic ductal cell
upper lobe of left lung
Top expressed in
spermatid
seminiferous tubule
lip
spermatocyte
morula
pharynx
nasopharynx
superior frontal gyrus
thymus
esophagus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
microtubule binding
Cellular component
cytosol
plasma membrane
cilium
cell projection
intracellular membrane-bounded organelle
ciliary basal body
cytoplasm
cytoskeleton
Biological process
sperm axoneme assembly
spermatogenesis
cell differentiation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
286207
227736
Ensembl
n/a
ENSMUSG00000038987
UniProt
Q5JU67
Q0VFX2
RefSeq (mRNA)
NM_001012502
NM_025619
RefSeq (protein)
NP_001012520
NP_079895
Location (UCSC)
n/a
Chr 2: 32.67 – 32.67 Mb
PubMed search
[2]
[3]
Wikidata
View/Edit Human
View/Edit Mouse
Cilia and flagella associated protein 157 (CFAP157) also known as chromosome 9 open reading frame 117 (c9orf117) is a protein that in humans is encoded by the CFAP157 gene.
CFAP157 gene is "specifically required during spermatogenesis for flagellum morphogenesis and sperm motility and may be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure,"[4] according to UniProt.
^ abcGRCm38: Ensembl release 89: ENSMUSG00000038987 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"CFAP157 - Cilia- and flagella-associated protein 157 - Homo sapiens (Human) - CFAP157 gene & protein". www.uniprot.org. Retrieved 2018-02-05.
157 (CFAP157) also known as chromosome 9 open reading frame 117 (c9orf117) is a protein that in humans is encoded by the CFAP157 gene. CFAP157 gene is...
Global Information
